2-Bromo-4-hydroxybenzoic acid

Name: 2-Bromo-4-hydroxybenzoic acid
Brand: Vaqora Chemicals
SKU: VQ-029936

About 2-Bromo-4-hydroxybenzoic acid

Listed under CAS 28547-28-6, 2-Bromo-4-hydroxybenzoic acid is a metabolite or degradation product of Crisaborole available from Vaqora Chemicals. With the molecular formula C7H5BrO3, it has a molar mass of 217.02 g/mol. It is also known as Benzoic acid, 2-bromo-4-hydroxy- or Brom-p-oxybenzoesaure.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Under GHS it is labelled “Danger”, so handle it with suitable PPE and consult the SDS.

It is used in metabolite identification, stability-indicating method development and impurity profiling of Crisaborole, as well as in QC testing and ANDA/DMF documentation. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Crisaborole

View every impurity, metabolite and intermediate we list for Crisaborole.

Crisaborole impurities

Specifications & identifiers

Chemical identifiers
Product name	2-Bromo-4-hydroxybenzoic acid
Catalogue No.	VQ-029936
CAS Number	28547-28-6
IUPAC name	2-bromo-4-hydroxybenzoic acid
Molecular formula	C₇H₅BrO₃
Molecular weight	217.02 g/mol
Exact mass	215.9422
Grade	Reference Standard
HSN code	38229090
InChIKey	POGXJMWDTFROTM-UHFFFAOYSA-N
SMILES	C1=CC(=C(C=C1O)Br)C(=O)O
PubChem CID	14797203

Physical properties
Physical form	Solid
LogP (XLogP3)	2.1
H-bond donors / acceptors	2 / 3
TPSA	57.5 Å²

Safety & hazard information (GHS)

Corrosive

Harmful / irritant

Signal word: Danger

Hazard statements

H318Causes serious eye damage
H335May cause respiratory irritation

Precautionary statements: P261, P264 + P265, P271, P280, P304 + P340, P305 + P354 + P338, P317, P319, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 2-Bromo-4-hydroxybenzoic acid?

The CAS Registry Number of 2-Bromo-4-hydroxybenzoic acid is 28547-28-6. It is also known as Benzoic acid, 2-bromo-4-hydroxy-, Brom-p-oxybenzoesaure.

What is the molecular formula and molecular weight of 2-Bromo-4-hydroxybenzoic acid?

2-Bromo-4-hydroxybenzoic acid has the molecular formula C7H5BrO3 and a molecular weight of 217.02 g/mol. Its IUPAC name is 2-bromo-4-hydroxybenzoic acid.

What is 2-Bromo-4-hydroxybenzoic acid used for?

2-Bromo-4-hydroxybenzoic acid is supplied as a characterised reference material related to Crisaborole. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 2-Bromo-4-hydroxybenzoic acid can I order?

We supply 2-Bromo-4-hydroxybenzoic acid in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 2-Bromo-4-hydroxybenzoic acid?

Yes. Every lot of 2-Bromo-4-hydroxybenzoic acid is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 2-Bromo-4-hydroxybenzoic acid be shipped internationally?

Yes. 2-Bromo-4-hydroxybenzoic acid is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.