Cediranib

Name: Cediranib
Brand: Vaqora Chemicals
SKU: VQ-043099

About Cediranib

Listed under CAS 288383-20-0, Cediranib is an API impurity reference standard available from Vaqora Chemicals. With the molecular formula C25H27FN4O3, it has a molar mass of 450.5 g/mol. The IUPAC name is 4-[(4-fluoro-2-methyl-1H-indol-5-yl)oxy]-6-methoxy-7-(3-pyrrolidin-1-ylpropoxy)quinazoline. It is also known as AZD-2171 or AZD 2171.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. It carries the GHS signal word “Danger” with 6 hazard statements. Review the Safety Data Sheet before use.

As a characterised impurity of the parent drug substance, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

We offer Cediranib in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Specifications & identifiers

Chemical identifiers
Product name	Cediranib
Catalogue No.	VQ-043099
CAS Number	288383-20-0
IUPAC name	4-[(4-fluoro-2-methyl-1H-indol-5-yl)oxy]-6-methoxy-7-(3-pyrrolidin-1-ylpropoxy)quinazoline
Molecular formula	C₂₅H₂₇FN₄O₃
Molecular weight	450.5 g/mol
Exact mass	450.2067
Grade	Reference Standard
HSN code	38229090
InChIKey	XXJWYDDUDKYVKI-UHFFFAOYSA-N
SMILES	CC1=CC2=C(N1)C=CC(=C2F)OC3=NC=NC4=CC(=C(C=C43)OC)OCCCN5CCCC5
PubChem CID	9933475

Physical properties
Physical form	Solid
LogP (XLogP3)	4.9
H-bond donors / acceptors	1 / 7
TPSA	72.5 Å²
Synonyms	AZD-2171, AZD 2171, Cediranib (AZD2171), 4-(4-Fluoro-2-methylindol-5-yloxy)-6-methoxy-7-[3-(pyrrolidin-1-yl)propoxy]quinazoline, Cediranib free base, 4-(4-fluoro-2-methyl-1H-indol-5-yloxy)-6-methoxy-7-(3-(pyrrolidin-1-yl)propoxy)quinazoline, Kinome_3318, Cediranib - AZD2171, 4-(4-fluoro-2-methylindol-5-yloxy)-6-methoxy-7-(3-(pyrrolidin-1-yl)propoxy)quinazoline, Cediranib,AZD2171, AZD2171, Cediranib, EX-A2039

Safety & hazard information (GHS)

Toxic

Harmful / irritant

Health hazard

Environmental hazard

Signal word: Danger

Hazard statements

H301Toxic if swallowed
H312Harmful in contact with skin
H315Causes skin irritation
H361Suspected of damaging fertility or the unborn child
H372Causes damage to organs through prolonged or repeated exposure
H410Very toxic to aquatic life with long lasting effects

Precautionary statements: P203, P260, P264, P270, P273, P280, P301 + P316, P302 + P352, P317, P318, P319, P321, P330, P332 + P317, P362 + P364, P391, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Cediranib?

The CAS Registry Number of Cediranib is 288383-20-0. It is also known as AZD-2171, AZD 2171, Cediranib (AZD2171).

What is the molecular formula and molecular weight of Cediranib?

Cediranib has the molecular formula C25H27FN4O3 and a molecular weight of 450.5 g/mol. Its IUPAC name is 4-[(4-fluoro-2-methyl-1H-indol-5-yl)oxy]-6-methoxy-7-(3-pyrrolidin-1-ylpropoxy)quinazoline.

Which grade and pack sizes of Cediranib can I order?

We supply Cediranib in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Cediranib?

Yes. Every lot of Cediranib is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Cediranib be shipped internationally?

Yes. Cediranib is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.