N'-(7-Chloro-5-phenyl-3H-benzo[e][1,4]diazepi… 28910-89-6

Name: N'-(7-Chloro-5-phenyl-3H-benzo[e][1,4]diazepin-2-yl)acetohydrazide
Brand: Vaqora Chemicals
SKU: VQ-035664

About N'-(7-Chloro-5-phenyl-3H-benzo[e][1,4]diazepin-2-yl)acetohydrazide

N'-(7-Chloro-5-phenyl-3H-benzo[e][1,4]diazepin-2-yl)acetohydrazide is an impurity of Alprazolam carrying the CAS registry number 28910-89-6. The compound has the formula C17H15ClN4O, corresponding to a molecular weight of 326.8 g/mol. Its systematic (IUPAC) name is N'-(7-chloro-5-phenyl-3H-1,4-benzodiazepin-2-yl)acetohydrazide.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

This Alprazolam impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies N'-(7-Chloro-5-phenyl-3H-benzo[e][1,4]diazepin-2-yl)acetohydrazide in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Alprazolam

View every impurity, metabolite and intermediate we list for Alprazolam.

Alprazolam impurities

Specifications & identifiers

Chemical identifiers
Product name	N'-(7-Chloro-5-phenyl-3H-benzo[e][1,4]diazepin-2-yl)acetohydrazide
Catalogue No.	VQ-035664
CAS Number	28910-89-6
IUPAC name	N'-(7-chloro-5-phenyl-3H-1,4-benzodiazepin-2-yl)acetohydrazide
Molecular formula	C₁₇H₁₅ClN₄O
Molecular weight	326.8 g/mol
Exact mass	326.0934
Grade	Reference Standard
HSN code	38229090
InChIKey	RIYMFZCORTVORQ-UHFFFAOYSA-N
SMILES	CC(=O)NNC1=NC2=C(C=C(C=C2)Cl)C(=NC1)C3=CC=CC=C3
PubChem CID	624374

Physical properties
Physical form	Solid
LogP (XLogP3)	2.6
H-bond donors / acceptors	2 / 3
TPSA	65.9 Å²
Synonyms	2-(2-acetylhydrazino)-7-chloro-5-phenyl-3H-1,4-benzodiazepine, Acetic acid, 2-(7-chloro-5-phenyl-3H-1,4-benzodiazepin-2-yl)hydrazide, 7-Chloro-5-phenyl-1,3-dihydro-2H-1,4-benzodiazepine-2 acetylhydrazone, N\'-(7-chloro-5-phenyl-3H-1,4-benzodiazepin-2-yl)acetohydrazide, N'-[(2E)-7-Chloro-5-phenyl-1,3-dihydro-2H-1,4-benzodiazepin-2-ylidene]acetohydrazide #

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P271, P280, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of N'-(7-Chloro-5-phenyl-3H-benzo[e][1,4]diazepin-2-yl)acetohydrazide?

The CAS Registry Number of N'-(7-Chloro-5-phenyl-3H-benzo[e][1,4]diazepin-2-yl)acetohydrazide is 28910-89-6. It is also known as 2-(2-acetylhydrazino)-7-chloro-5-phenyl-3H-1,4-benzodiazepine, Acetic acid, 2-(7-chloro-5-phenyl-3H-1,4-benzodiazepin-2-yl)hydrazide, 7-Chloro-5-phenyl-1,3-dihydro-2H-1,4-benzodiazepine-2 acetylhydrazone.

What is the molecular formula and molecular weight of N'-(7-Chloro-5-phenyl-3H-benzo[e][1,4]diazepin-2-yl)acetohydrazide?

N'-(7-Chloro-5-phenyl-3H-benzo[e][1,4]diazepin-2-yl)acetohydrazide has the molecular formula C17H15ClN4O and a molecular weight of 326.8 g/mol. Its IUPAC name is N'-(7-chloro-5-phenyl-3H-1,4-benzodiazepin-2-yl)acetohydrazide.

What is N'-(7-Chloro-5-phenyl-3H-benzo[e][1,4]diazepin-2-yl)acetohydrazide used for?

N'-(7-Chloro-5-phenyl-3H-benzo[e][1,4]diazepin-2-yl)acetohydrazide is supplied as a characterised reference material related to Alprazolam. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of N'-(7-Chloro-5-phenyl-3H-benzo[e][1,4]diazepin-2-yl)acetohydrazide can I order?

We supply N'-(7-Chloro-5-phenyl-3H-benzo[e][1,4]diazepin-2-yl)acetohydrazide in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with N'-(7-Chloro-5-phenyl-3H-benzo[e][1,4]diazepin-2-yl)acetohydrazide?

Yes. Every lot of N'-(7-Chloro-5-phenyl-3H-benzo[e][1,4]diazepin-2-yl)acetohydrazide is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can N'-(7-Chloro-5-phenyl-3H-benzo[e][1,4]diazepin-2-yl)acetohydrazide be shipped internationally?

Yes. N'-(7-Chloro-5-phenyl-3H-benzo[e][1,4]diazepin-2-yl)acetohydrazide is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.