N-Desmethyl Netupitant

Name: N-Desmethyl Netupitant
Brand: Vaqora Chemicals
SKU: VQ-023235

About N-Desmethyl Netupitant

Vaqora Chemicals supplies N-Desmethyl Netupitant, a metabolite or degradation product of Netupitant registered under CAS number 290296-72-9. The compound has the formula C29H30F6N4O, corresponding to a molecular weight of 564.6 g/mol. Its systematic (IUPAC) name is 2-[3,5-bis(trifluoromethyl)phenyl]-N,2-dimethyl-N-[4-(2-methylphenyl)-6-piperazin-1-yl-3-pyridinyl]propanamide. Common synonyms include Netupitant Metabolite M1 and Netupitant metabolite N-desmethyl Netupitant.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Good laboratory practice and suitable PPE are recommended during handling.

It is used in metabolite identification, stability-indicating method development and impurity profiling of Netupitant, as well as in QC testing and ANDA/DMF documentation. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, N-Desmethyl Netupitant is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Netupitant

View every impurity, metabolite and intermediate we list for Netupitant.

Netupitant impurities

Specifications & identifiers

Chemical identifiers
Product name	N-Desmethyl Netupitant
Catalogue No.	VQ-023235
CAS Number	290296-72-9
IUPAC name	2-[3,5-bis(trifluoromethyl)phenyl]-N,2-dimethyl-N-[4-(2-methylphenyl)-6-piperazin-1-yl-3-pyridinyl]propanamide
Molecular formula	C₂₉H₃₀F₆N₄O
Molecular weight	564.6 g/mol
Exact mass	564.2324
Grade	Reference Standard
HSN code	38229090
InChIKey	SRVSDBHUBFLSFE-UHFFFAOYSA-N
SMILES	CC1=CC=CC=C1C2=CC(=NC=C2N(C)C(=O)C(C)(C)C3=CC(=CC(=C3)C(F)(F)F)C(F)(F)F)N4CCNCC4
PubChem CID	9915918

Physical properties
Physical form	Solid
LogP (XLogP3)	6.3
H-bond donors / acceptors	1 / 10
TPSA	48.5 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of N-Desmethyl Netupitant?

The CAS Registry Number of N-Desmethyl Netupitant is 290296-72-9. It is also known as Netupitant Metabolite M1, Netupitant metabolite N-desmethyl Netupitant, EX-A3289.

What is the molecular formula and molecular weight of N-Desmethyl Netupitant?

N-Desmethyl Netupitant has the molecular formula C29H30F6N4O and a molecular weight of 564.6 g/mol. Its IUPAC name is 2-[3,5-bis(trifluoromethyl)phenyl]-N,2-dimethyl-N-[4-(2-methylphenyl)-6-piperazin-1-yl-3-pyridinyl]propanamide.

What is N-Desmethyl Netupitant used for?

N-Desmethyl Netupitant is supplied as a characterised reference material related to Netupitant. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of N-Desmethyl Netupitant can I order?

We supply N-Desmethyl Netupitant in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with N-Desmethyl Netupitant?

Yes. Every lot of N-Desmethyl Netupitant is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can N-Desmethyl Netupitant be shipped internationally?

Yes. We export N-Desmethyl Netupitant worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.