Guanfacine

About Guanfacine

Guanfacine is a high-purity reference standard of Guanfacine carrying the CAS registry number 29110-47-2. Its molecular formula is C9H9Cl2N3O and its molecular weight is 246.09 g/mol. The IUPAC name is N-(diaminomethylidene)-2-(2,6-dichlorophenyl)acetamide. It is also known as N-amidino-2-(2,6-dichlorophenyl)acetamide or Estulic.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. It carries the GHS signal word “Danger” with 4 hazard statements. Review the Safety Data Sheet before use.

Laboratories use this Guanfacine standard for identity and assay testing, system suitability checks and method validation supporting ANDA and DMF filings. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

We offer Guanfacine in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Guanfacine

View every impurity, metabolite and intermediate we list for Guanfacine.

Guanfacine impurities

Specifications & identifiers

Chemical identifiers
Product name	Guanfacine
Catalogue No.	VQ-043188
CAS Number	29110-47-2
IUPAC name	N-(diaminomethylidene)-2-(2,6-dichlorophenyl)acetamide
Molecular formula	C₉H₉Cl₂N₃O
Molecular weight	246.09 g/mol
Exact mass	245.0123
Grade	Reference Standard
HSN code	38229090
InChIKey	INJOMKTZOLKMBF-UHFFFAOYSA-N
SMILES	C1=CC(=C(C(=C1)Cl)CC(=O)N=C(N)N)Cl
PubChem CID	3519

Physical properties
Physical form	Solid
LogP (XLogP3)	2
H-bond donors / acceptors	2 / 1
TPSA	81.5 Å²
Synonyms	N-carbamimidoyl-2-(2,6-dichlorophenyl)acetamide, Benzeneacetamide, N-(aminoiminomethyl)-2,6-dichloro-, N-amidino-2-(2,6-dichlorophenyl)acetamide, Estulic, Guanfacine hydrochloride (Salt/Mix), SPD 503, Tenex (Salt/Mix), Estulic (Salt/Mix), LON 798 (Salt/Mix), (2,6-dichlorophenylacetyl)-guanidine, [(2,6-dichlorophenyl)acetyl]guanidine, N-(diaminomethylene)-2-(2,6-dichlorophenyl)acetamide

Safety & hazard information (GHS)

Toxic

Health hazard

Environmental hazard

Signal word: Danger

Hazard statements

H301Toxic if swallowed
H361Suspected of damaging fertility or the unborn child
H373May causes damage to organs through prolonged or repeated exposure
H411Toxic to aquatic life with long lasting effects

Precautionary statements: P203, P260, P264, P270, P273, P280, P301 + P316, P318, P319, P321, P330, P391, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Guanfacine?

The CAS Registry Number of Guanfacine is 29110-47-2. It is also known as N-carbamimidoyl-2-(2,6-dichlorophenyl)acetamide, Benzeneacetamide, N-(aminoiminomethyl)-2,6-dichloro-, N-amidino-2-(2,6-dichlorophenyl)acetamide.

What is the molecular formula and molecular weight of Guanfacine?

Guanfacine has the molecular formula C9H9Cl2N3O and a molecular weight of 246.09 g/mol. Its IUPAC name is N-(diaminomethylidene)-2-(2,6-dichlorophenyl)acetamide.

What is Guanfacine used for?

Guanfacine is supplied as a characterised reference material related to Guanfacine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Guanfacine can I order?

We supply Guanfacine in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Guanfacine?

Yes. Every lot of Guanfacine is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Guanfacine be shipped internationally?

Yes. Guanfacine is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.