N-(5-Oxo-L-prolyl)-L-glutamic Acid

About N-(5-Oxo-L-prolyl)-L-glutamic Acid

N-(5-Oxo-L-prolyl)-L-glutamic Acid is an impurity of Pidotimod carrying the CAS registry number 29227-92-7. With the molecular formula C10H14N2O6, it has a molar mass of 258.23 g/mol. Systematically, it is named (2S)-2-[[(2S)-5-oxopyrrolidine-2-carbonyl]amino]pentanedioic acid. Alternative names: Pyroglutamylglutamic acid and L-Glutamic acid, 5-oxo-L-prolyl-.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. It carries the GHS signal word “Warning” with 3 hazard statements. Review the Safety Data Sheet before use.

As a characterised impurity of Pidotimod, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

We offer N-(5-Oxo-L-prolyl)-L-glutamic Acid in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Pidotimod

View every impurity, metabolite and intermediate we list for Pidotimod.

Pidotimod impurities

Specifications & identifiers

Chemical identifiers
Product name	N-(5-Oxo-L-prolyl)-L-glutamic Acid
Catalogue No.	VQ-032788
CAS Number	29227-92-7
IUPAC name	(2S)-2-[[(2S)-5-oxopyrrolidine-2-carbonyl]amino]pentanedioic acid
Molecular formula	C₁₀H₁₄N₂O₆
Molecular weight	258.23 g/mol
Exact mass	258.0852
Grade	Reference Standard
HSN code	38229090
InChIKey	YRUFRJRFQFBNQR-WDSKDSINSA-N
SMILES	C1CC(=O)N[C@@H]1C(=O)N[C@@H](CCC(=O)O)C(=O)O
PubChem CID	70530537

Physical properties
Physical form	Solid
LogP (XLogP3)	-1.5
H-bond donors / acceptors	4 / 6
TPSA	133 Å²
Synonyms	(2S)-2-{[(2S)-5-oxopyrrolidin-2-yl]formamido}pentanedioic acid, (2S)-2-(((2S)-5-Oxopyrrolidin-2-yl)formamido)pentanedioic acid, Pyroglutamylglutamic acid, L-Glutamic acid, 5-oxo-L-prolyl-, 5-Oxo-L-prolyl-L-glutamic acid, (S)-2-((S)-5-Oxopyrrolidine-2-carboxamido)pentanedioic acid, Glutamic acid, N-L-pyroglutamyl-, L-, L-Glutamic acid, N-(5-oxo-L-prolyl)-, Glutamic acid, N-(5-oxo-L-prolyl)-, L-, (S)-2-[(S)-5-Oxopyrrolidine-2-carboxamido]pentanedioic Acid

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P271, P280, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of N-(5-Oxo-L-prolyl)-L-glutamic Acid?

The CAS Registry Number of N-(5-Oxo-L-prolyl)-L-glutamic Acid is 29227-92-7. It is also known as (2S)-2-{[(2S)-5-oxopyrrolidin-2-yl]formamido}pentanedioic acid, (2S)-2-(((2S)-5-Oxopyrrolidin-2-yl)formamido)pentanedioic acid, Pyroglutamylglutamic acid.

What is the molecular formula and molecular weight of N-(5-Oxo-L-prolyl)-L-glutamic Acid?

N-(5-Oxo-L-prolyl)-L-glutamic Acid has the molecular formula C10H14N2O6 and a molecular weight of 258.23 g/mol. Its IUPAC name is (2S)-2-[[(2S)-5-oxopyrrolidine-2-carbonyl]amino]pentanedioic acid.

What is N-(5-Oxo-L-prolyl)-L-glutamic Acid used for?

N-(5-Oxo-L-prolyl)-L-glutamic Acid is supplied as a characterised reference material related to Pidotimod. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of N-(5-Oxo-L-prolyl)-L-glutamic Acid can I order?

We supply N-(5-Oxo-L-prolyl)-L-glutamic Acid in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with N-(5-Oxo-L-prolyl)-L-glutamic Acid?

Yes. Every lot of N-(5-Oxo-L-prolyl)-L-glutamic Acid is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can N-(5-Oxo-L-prolyl)-L-glutamic Acid be shipped internationally?

Yes. N-(5-Oxo-L-prolyl)-L-glutamic Acid is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.