1,4-Benzodioxan-6-carboxaldehyde

About 1,4-Benzodioxan-6-carboxaldehyde

1,4-Benzodioxan-6-carboxaldehyde is a process intermediate or related compound of Eliglustat carrying the CAS registry number 29668-44-8. Formula C9H8O3, molecular weight 164.16 g/mol. The IUPAC name is 2,3-dihydro-1,4-benzodioxine-6-carbaldehyde. Alternative names: 2,3-Dihydro-1,4-benzodioxin-6-carboxaldehyde and 1,4-Benzodioxan-7-formaldehyde.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

Process chemists and analysts use it when developing synthetic routes to Eliglustat, tracking process-related impurities and validating analytical methods. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, 1,4-Benzodioxan-6-carboxaldehyde is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

API route development
Impurity fate & purge studies
Analytical method development

Industries

Related to Eliglustat

View every impurity, metabolite and intermediate we list for Eliglustat.

Eliglustat impurities

Specifications & identifiers

Chemical identifiers
Product name	1,4-Benzodioxan-6-carboxaldehyde
Catalogue No.	VQ-012822
CAS Number	29668-44-8
IUPAC name	2,3-dihydro-1,4-benzodioxine-6-carbaldehyde
Molecular formula	C₉H₈O₃
Molecular weight	164.16 g/mol
Exact mass	164.0473
Grade	Reference Standard
InChIKey	CWKXDPPQCVWXAG-UHFFFAOYSA-N
SMILES	C1COC2=C(O1)C=CC(=C2)C=O
PubChem CID	248127

Physical properties
Physical form	Solid
LogP (XLogP3)	1
H-bond donors / acceptors	0 / 3
TPSA	35.5 Å²
Synonyms	2,3-Dihydro-1,4-benzodioxin-6-carboxaldehyde, 1,4-Benzodioxan-6-carboxaldehyde, 1,4-Benzodioxan-7-formaldehyde, 1,4-Benzodioxane-6-aldehyde, 2,3-Dihydro-1,4-benzodioxan-6-carboxaldehyde, 2,3-Dihydro-1,4-benzodioxin-6-aldehyde, 2,3-Dihydrobenzo[b][1,4]dioxine-6-carboxaldehyde, 3,4-Ethylenedioxybenzaldehyde, 2,3-Dihydro-1,4-benzodioxin-6-carbaldehyde, 2,3-dihydrobenzo[b][1,4]dioxine-6-carbaldehyde, 1,4-Benzodioxane-6-carboxaldehyde, 1,4-Benzodioxin-6-carboxaldehyde, 2,3-dihydro-

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P271, P280, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 1,4-Benzodioxan-6-carboxaldehyde?

The CAS Registry Number of 1,4-Benzodioxan-6-carboxaldehyde is 29668-44-8. It is also known as 2,3-Dihydro-1,4-benzodioxin-6-carboxaldehyde, 1,4-Benzodioxan-6-carboxaldehyde, 1,4-Benzodioxan-7-formaldehyde.

What is the molecular formula and molecular weight of 1,4-Benzodioxan-6-carboxaldehyde?

1,4-Benzodioxan-6-carboxaldehyde has the molecular formula C9H8O3 and a molecular weight of 164.16 g/mol. Its IUPAC name is 2,3-dihydro-1,4-benzodioxine-6-carbaldehyde.

What is 1,4-Benzodioxan-6-carboxaldehyde used for?

1,4-Benzodioxan-6-carboxaldehyde is supplied as a characterised reference material related to Eliglustat. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 1,4-Benzodioxan-6-carboxaldehyde can I order?

We supply 1,4-Benzodioxan-6-carboxaldehyde in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 1,4-Benzodioxan-6-carboxaldehyde?

Yes. Every lot of 1,4-Benzodioxan-6-carboxaldehyde is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 1,4-Benzodioxan-6-carboxaldehyde be shipped internationally?

Yes. 1,4-Benzodioxan-6-carboxaldehyde is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.