2-Amino-4-thiazoleacetic Acid

About 2-Amino-4-thiazoleacetic Acid

2-Amino-4-thiazoleacetic Acid is a process intermediate or related compound of Mirabegron carrying the CAS registry number 29676-71-9. Formula C5H6N2O2S, molecular weight 158.18 g/mol. Its systematic (IUPAC) name is 2-(2-amino-1,3-thiazol-4-yl)acetic acid. Alternative names: (2-Amino-1,3-thiazol-4-yl)acetic Acid and (2-Amino-4-thiazoyl)acetic Acid.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

Process chemists and analysts use it when developing synthetic routes to Mirabegron, tracking process-related impurities and validating analytical methods. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide. Stock is available for quick dispatch.

Typical applications

API route development
Impurity fate & purge studies
Analytical method development

Industries

Related to Mirabegron

View every impurity, metabolite and intermediate we list for Mirabegron.

Mirabegron impurities

Specifications & identifiers

Chemical identifiers
Product name	2-Amino-4-thiazoleacetic Acid
Catalogue No.	VQ-012927
CAS Number	29676-71-9
IUPAC name	2-(2-amino-1,3-thiazol-4-yl)acetic acid
Molecular formula	C₅H₆N₂O₂S
Molecular weight	158.18 g/mol
Exact mass	158.015
Grade	Reference Standard
HSN code	2933
InChIKey	DYCLHZPOADTVKK-UHFFFAOYSA-N
SMILES	C1=C(N=C(S1)N)CC(=O)O
PubChem CID	34665

Physical properties
Physical form	Solid
LogP (XLogP3)	0.1
H-bond donors / acceptors	2 / 5
TPSA	104 Å²
Synonyms	(2-Amino-1,3-thiazol-4-yl)acetic Acid, (2-Amino-4-thiazoyl)acetic Acid, 2-(2-Amino-4-thiazolyl)acetic Acid, 2-Amino-4-thiazolylacetic Acid, 2-Aminothiazole-4-acetic Acid, SQ 272, 2-(2-Aminothiazol-4-yl)acetic acid, 2-Aminothiazol-4-acetic acid, (2-Aminothiazole-4-yl)acetic acid, 4-Thiazoleacetic acid, 2-amino-, (2-Amino-4-thiazolyl)acetic acid, 2-amino-4-thiazole acetic acid

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P271, P280, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 2-Amino-4-thiazoleacetic Acid?

The CAS Registry Number of 2-Amino-4-thiazoleacetic Acid is 29676-71-9. It is also known as (2-Amino-1,3-thiazol-4-yl)acetic Acid, (2-Amino-4-thiazoyl)acetic Acid, 2-(2-Amino-4-thiazolyl)acetic Acid.

What is the molecular formula and molecular weight of 2-Amino-4-thiazoleacetic Acid?

2-Amino-4-thiazoleacetic Acid has the molecular formula C5H6N2O2S and a molecular weight of 158.18 g/mol. Its IUPAC name is 2-(2-amino-1,3-thiazol-4-yl)acetic acid.

What is 2-Amino-4-thiazoleacetic Acid used for?

2-Amino-4-thiazoleacetic Acid is supplied as a characterised reference material related to Mirabegron. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 2-Amino-4-thiazoleacetic Acid can I order?

We supply 2-Amino-4-thiazoleacetic Acid in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg, 500 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 2-Amino-4-thiazoleacetic Acid?

Yes. Every lot of 2-Amino-4-thiazoleacetic Acid is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 2-Amino-4-thiazoleacetic Acid be shipped internationally?

Yes. 2-Amino-4-thiazoleacetic Acid is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.