Aripiprazole Nitroso Impurity 1

About Aripiprazole Nitroso Impurity 1

Aripiprazole Nitroso Impurity 1 is a nitrosamine impurity of Aripiprazole carrying the CAS registry number 2989508-28-1. With the molecular formula C10H11Cl2N3O, it has a molar mass of 260.12 g/mol. Systematically, it is named 1-(2,3-dichlorophenyl)-4-nitrosopiperazine. Common synonyms include Aripiprazole Nitroso Impurity 62 and 1-(2,3-Dichlorophenyl)-4-nitroso Piperazine.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

It is used as a reference standard for trace-level detection and quantitation of nitrosamine impurities by LC-MS/MS or GC-MS, supporting nitrosamine risk assessments for Aripiprazole, method validation (AMV) and regulatory filings. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Aripiprazole Nitroso Impurity 1 is dispatched with a Certificate of Analysis (COA) to destinations worldwide. Stock is available for quick dispatch.

Typical applications

Nitrosamine risk assessment
Trace LC-MS/MS quantitation
Method validation (AMV)
Regulatory submissions

Industries

Related to Aripiprazole

View every impurity, metabolite and intermediate we list for Aripiprazole.

Aripiprazole impurities

Specifications & identifiers

Chemical identifiers
Product name	Aripiprazole Nitroso Impurity 1
Catalogue No.	VQ-006816
CAS Number	2989508-28-1
IUPAC name	1-(2,3-dichlorophenyl)-4-nitrosopiperazine
Molecular formula	C₁₀H₁₁Cl₂N₃O
Molecular weight	260.12 g/mol
Exact mass	259.0279
Grade	Reference Standard
HSN code	38229090
InChIKey	IBXYJRGCUQRECX-UHFFFAOYSA-N
SMILES	C1CN(CCN1C2=C(C(=CC=C2)Cl)Cl)N=O
PubChem CID	165605069

Physical properties
Physical form	Solid
LogP (XLogP3)	3
H-bond donors / acceptors	0 / 4
TPSA	35.9 Å²

Safety & hazard information (GHS)

Harmful / irritant

Health hazard

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H312Harmful in contact with skin
H332Harmful if inhaled
H351Suspected of causing cancer

Precautionary statements: P203, P261, P264, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P317, P318, P321, P330, P362 + P364, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Aripiprazole Nitroso Impurity 1?

The CAS Registry Number of Aripiprazole Nitroso Impurity 1 is 2989508-28-1. It is also known as Aripiprazole Nitroso Impurity 62, 1-(2,3-Dichlorophenyl)-4-nitroso Piperazine, Piperazine, 1-(2,3-dichlorophenyl)-4-nitroso-.

What is the molecular formula and molecular weight of Aripiprazole Nitroso Impurity 1?

Aripiprazole Nitroso Impurity 1 has the molecular formula C10H11Cl2N3O and a molecular weight of 260.12 g/mol. Its IUPAC name is 1-(2,3-dichlorophenyl)-4-nitrosopiperazine.

What is Aripiprazole Nitroso Impurity 1 used for?

Aripiprazole Nitroso Impurity 1 is supplied as a characterised reference material related to Aripiprazole. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Aripiprazole Nitroso Impurity 1 can I order?

We supply Aripiprazole Nitroso Impurity 1 in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg, 500 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Aripiprazole Nitroso Impurity 1?

Yes. Every lot of Aripiprazole Nitroso Impurity 1 is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Aripiprazole Nitroso Impurity 1 be shipped internationally?

Yes. Aripiprazole Nitroso Impurity 1 is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.