Polmacoxib

About Polmacoxib

Polmacoxib is a high-purity reference standard of Polmacoxib carrying the CAS registry number 301692-76-2. The compound has the formula C18H16FNO4S, corresponding to a molecular weight of 361.4 g/mol. The IUPAC name is 4-[3-(3-fluorophenyl)-5,5-dimethyl-4-oxofuran-2-yl]benzenesulfonamide. Alternative names: Acelex (S. Korea) and EX-A601.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Good laboratory practice and suitable PPE are recommended during handling.

Laboratories use this Polmacoxib standard for identity and assay testing, system suitability checks and method validation supporting ANDA and DMF filings. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

We offer Polmacoxib in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Polmacoxib

View every impurity, metabolite and intermediate we list for Polmacoxib.

Polmacoxib impurities

Specifications & identifiers

Chemical identifiers
Product name	Polmacoxib
Catalogue No.	VQ-033240
CAS Number	301692-76-2
IUPAC name	4-[3-(3-fluorophenyl)-5,5-dimethyl-4-oxofuran-2-yl]benzenesulfonamide
Molecular formula	C₁₈H₁₆FNO₄S
Molecular weight	361.4 g/mol
Exact mass	361.0784
Grade	Reference Standard
HSN code	38229090
InChIKey	IJWPAFMIFNSIGD-UHFFFAOYSA-N
SMILES	CC1(C(=O)C(=C(O1)C2=CC=C(C=C2)S(=O)(=O)N)C3=CC(=CC=C3)F)C
PubChem CID	9841854

Physical properties
Physical form	Solid
LogP (XLogP3)	2.6
H-bond donors / acceptors	1 / 6
TPSA	94.8 Å²
Synonyms	4-(3-(3-Fluorophenyl)-5,5-dimethyl-4-oxo-4,5-dihydrofuran-2-yl)-benzenesulfonamide, Benzenesulfonamide, 4-(3-(3-fluorophenyl)-4,5-dihydro-5,5-dimethyl-4-oxo-2-furanyl)-, 4-(3-(3-fluorophenyl)-5,5-dimethyl-4-oxofuran-2-yl)benzenesulfonamide, 4-[3-(3-Fluorophenyl)-5,5-dimethyl-4-oxo-4,5-dihydrofuran-2-yl]-benzenesulfonamide, 4-(3-(3-fluorophenyl)-5,5-dimethyl-4-oxo-4,5-dihydrofuran-2-yl)benzene-1-sulfonamide, 4-(3-(3-fluorophenyl)-5,5-dimethyl-4-oxo-4,5-dihydrofuran-2-yl)benzenesulfonamide, 4-[3-(3-Fluorophenyl)-5,5-Dimethyl-4-Oxidanylidene-Furan-2-Yl]benzenesulfonamide, 4-[3-(3-Fluorophenyl)-5,5-dimethyl-4-oxo-4,5-dihydrofuran-2-yl]benzenesulfonamide, Acelex (S. Korea), EX-A601, 4-[3-(3-fluorophenyl)-5,5-dimethyl-4-oxo-2-furyl]benzenesulfonamide, 5-{4-(aminosulfonyl)phenyl}-2,2-dimethyl-4-(3-fluorophenyl)-3(2H)-furanone

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Polmacoxib?

The CAS Registry Number of Polmacoxib is 301692-76-2. It is also known as 4-(3-(3-Fluorophenyl)-5,5-dimethyl-4-oxo-4,5-dihydrofuran-2-yl)-benzenesulfonamide, Benzenesulfonamide, 4-(3-(3-fluorophenyl)-4,5-dihydro-5,5-dimethyl-4-oxo-2-furanyl)-, 4-(3-(3-fluorophenyl)-5,5-dimethyl-4-oxofuran-2-yl)benzenesulfonamide.

What is the molecular formula and molecular weight of Polmacoxib?

Polmacoxib has the molecular formula C18H16FNO4S and a molecular weight of 361.4 g/mol. Its IUPAC name is 4-[3-(3-fluorophenyl)-5,5-dimethyl-4-oxofuran-2-yl]benzenesulfonamide.

What is Polmacoxib used for?

Polmacoxib is supplied as a characterised reference material related to Polmacoxib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Polmacoxib can I order?

We supply Polmacoxib in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Polmacoxib?

Yes. Every lot of Polmacoxib is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Polmacoxib be shipped internationally?

Yes. We export Polmacoxib worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.