Ezetimibe Desfluoro Impurity

Name: Ezetimibe Desfluoro Impurity
Brand: Vaqora Chemicals
SKU: VQ-004957

About Ezetimibe Desfluoro Impurity

Ezetimibe Desfluoro Impurity is an impurity of Ezetimibe carrying the CAS registry number 302781-98-2. Its molecular formula is C24H22FNO3 and its molecular weight is 391.4 g/mol. Systematically, it is named (3R,4S)-3-[(3S)-3-(4-fluorophenyl)-3-hydroxypropyl]-4-(4-hydroxyphenyl)-1-phenylazetidin-2-one. Alternative names: Desfluoroaniline analog (USP) and Desfluoro Ezetimibe.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. It carries the GHS signal word “Warning” with 5 hazard statements. Review the Safety Data Sheet before use.

As a characterised impurity of Ezetimibe, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Ezetimibe Desfluoro Impurity in 10 mg, 25 mg and 50 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide. This item is currently in stock for prompt dispatch.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Ezetimibe

View every impurity, metabolite and intermediate we list for Ezetimibe.

Ezetimibe impurities

Specifications & identifiers

Chemical identifiers
Product name	Ezetimibe Desfluoro Impurity
Catalogue No.	VQ-004957
CAS Number	302781-98-2
IUPAC name	(3R,4S)-3-[(3S)-3-(4-fluorophenyl)-3-hydroxypropyl]-4-(4-hydroxyphenyl)-1-phenylazetidin-2-one
Molecular formula	C₂₄H₂₂FNO₃
Molecular weight	391.4 g/mol
Exact mass	391.1584
Grade	Reference Standard
HSN code	38229090
InChIKey	YWZUFJFIXFJKBD-XPWALMASSA-N
SMILES	C1=CC=C(C=C1)N2[C@@H]([C@H](C2=O)CC[C@@H](C3=CC=C(C=C3)F)O)C4=CC=C(C=C4)O
PubChem CID	58827445

Physical properties
Physical form	Solid
LogP (XLogP3)	3.9
H-bond donors / acceptors	2 / 4
TPSA	60.8 Å²
Synonyms	Desfluoroaniline analog (USP), Desfluoro Ezetimibe, Desfluoro-ezetimibe, Ezetimibe Desfluoroaniline analog, Ezetimibe-5, 1-Desfluoro EzetiMibe, EzetiMibe Desfluoro Analog, Ezetimibe Desfluoroaniline Analog (Usp), Ezetimibe Impurity I

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H312Harmful in contact with skin
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled

Precautionary statements: P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P317, P321, P330, P332 + P317, P337 + P317, P362 + P364, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Ezetimibe Desfluoro Impurity?

The CAS Registry Number of Ezetimibe Desfluoro Impurity is 302781-98-2. It is also known as Desfluoroaniline analog (USP), Desfluoro Ezetimibe, Desfluoro-ezetimibe.

What is the molecular formula and molecular weight of Ezetimibe Desfluoro Impurity?

Ezetimibe Desfluoro Impurity has the molecular formula C24H22FNO3 and a molecular weight of 391.4 g/mol. Its IUPAC name is (3R,4S)-3-[(3S)-3-(4-fluorophenyl)-3-hydroxypropyl]-4-(4-hydroxyphenyl)-1-phenylazetidin-2-one.

What is Ezetimibe Desfluoro Impurity used for?

Ezetimibe Desfluoro Impurity is supplied as a characterised reference material related to Ezetimibe. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Ezetimibe Desfluoro Impurity can I order?

We supply Ezetimibe Desfluoro Impurity in Reference Standard grade, in 10 mg, 25 mg, 50 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Ezetimibe Desfluoro Impurity?

Yes. Every lot of Ezetimibe Desfluoro Impurity is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Ezetimibe Desfluoro Impurity be shipped internationally?

Yes. Ezetimibe Desfluoro Impurity is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.