N-Desmethyl Clomipramine

Name: N-Desmethyl Clomipramine
Brand: Vaqora Chemicals
SKU: VQ-036394

About N-Desmethyl Clomipramine

Vaqora Chemicals supplies N-Desmethyl Clomipramine, a metabolite or degradation product of Clomipramine registered under CAS number 303-48-0. The compound has the formula C18H21ClN2, corresponding to a molecular weight of 300.8 g/mol. Its systematic (IUPAC) name is 3-(2-chloro-5,6-dihydrobenzo[b][1]benzazepin-11-yl)-N-methylpropan-1-amine. Alternative names: Desmethyl Clomipramine and Desmethylclomipramine.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

Analytical teams use this compound to identify metabolites and degradants of Clomipramine, to validate stability-indicating methods (AMV) and to support QC and regulatory filings. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, N-Desmethyl Clomipramine is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Clomipramine

View every impurity, metabolite and intermediate we list for Clomipramine.

Clomipramine impurities

Specifications & identifiers

Chemical identifiers
Product name	N-Desmethyl Clomipramine
Catalogue No.	VQ-036394
CAS Number	303-48-0
IUPAC name	3-(2-chloro-5,6-dihydrobenzo[b][1]benzazepin-11-yl)-N-methylpropan-1-amine
Molecular formula	C₁₈H₂₁ClN₂
Molecular weight	300.8 g/mol
Exact mass	300.1393
Grade	Reference Standard
HSN code	38229090
InChIKey	VPIXQGUBUKFLRF-UHFFFAOYSA-N
SMILES	CNCCCN1C2=CC=CC=C2CCC3=C1C=C(C=C3)Cl
PubChem CID	622606

Physical properties
Physical form	Solid
LogP (XLogP3)	4.7
H-bond donors / acceptors	1 / 2
TPSA	15.3 Å²
Synonyms	Desmethyl Clomipramine, Desmethylclomipramine, Norclomipramine, Demethylchlorimipramine, Desmethylchlorimipramine, N-Demethylclomipramine, 5H-Dibenz[b,f]azepine-5-propanamine, 3-chloro-10,11-dihydro-N-methyl-, 5H-Dibenz(b,f)azepine-5-propanamine, 3-chloro-10,11-dihydro-N-methyl-, chlordesipramine, 3-(3-chloro-10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)-N-methylpropan-1-amine

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302+H312+H332Harmful if swallowed, in contact with skin or if inhaled
H302Harmful if swallowed
H312Harmful in contact with skin
H332Harmful if inhaled

Precautionary statements: P261, P264, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P317, P321, P330, P362 + P364, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of N-Desmethyl Clomipramine?

The CAS Registry Number of N-Desmethyl Clomipramine is 303-48-0. It is also known as Desmethyl Clomipramine, Desmethylclomipramine, Norclomipramine.

What is the molecular formula and molecular weight of N-Desmethyl Clomipramine?

N-Desmethyl Clomipramine has the molecular formula C18H21ClN2 and a molecular weight of 300.8 g/mol. Its IUPAC name is 3-(2-chloro-5,6-dihydrobenzo[b][1]benzazepin-11-yl)-N-methylpropan-1-amine.

What is N-Desmethyl Clomipramine used for?

N-Desmethyl Clomipramine is supplied as a characterised reference material related to Clomipramine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of N-Desmethyl Clomipramine can I order?

We supply N-Desmethyl Clomipramine in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with N-Desmethyl Clomipramine?

Yes. Every lot of N-Desmethyl Clomipramine is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can N-Desmethyl Clomipramine be shipped internationally?

Yes. N-Desmethyl Clomipramine is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.