21-Acetoxy-11beta -hydroxypregna-1,4,16-trien… 3044-42-6

Name: 21-Acetoxy-11beta -hydroxypregna-1,4,16-triene-3,20-dione
Brand: Vaqora Chemicals
SKU: VQ-021010

About 21-Acetoxy-11beta -hydroxypregna-1,4,16-triene-3,20-dione

21-Acetoxy-11beta -hydroxypregna-1,4,16-triene-3,20-dione (CAS 3044-42-6) is an impurity of Budesonide offered by Vaqora Chemicals. The compound has the formula C23H28O5, corresponding to a molecular weight of 384.5 g/mol.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. It carries the GHS signal word “Warning” with 2 hazard statements. Review the Safety Data Sheet before use.

Pharmaceutical QC and development laboratories use this impurity standard of Budesonide to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

We offer 21-Acetoxy-11beta -hydroxypregna-1,4,16-triene-3,20-dione in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Budesonide

View every impurity, metabolite and intermediate we list for Budesonide.

Budesonide impurities

Specifications & identifiers

Chemical identifiers
Product name	21-Acetoxy-11beta -hydroxypregna-1,4,16-triene-3,20-dione
Catalogue No.	VQ-021010
CAS Number	3044-42-6
IUPAC name	[2-[(8S,9S,10R,11S,13S,14S)-11-hydroxy-10,13-dimethyl-3-oxo-6,7,8,9,11,12,14,15-octahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethyl] acetate
Molecular formula	C₂₃H₂₈O₅
Molecular weight	384.5 g/mol
Exact mass	384.1937
Grade	Reference Standard
HSN code	38229090
InChIKey	ABGUZAVIFZZDDZ-MHYQPVDNSA-N
SMILES	CC(=O)OCC(=O)C1=CC[C@@H]2[C@@]1(C[C@@H]([C@H]3[C@H]2CCC4=CC(=O)C=C[C@]34C)O)C
PubChem CID	102365

Physical properties
Physical form	Solid
LogP (XLogP3)	2.7
H-bond donors / acceptors	1 / 5
TPSA	80.7 Å²
Synonyms	11beta,21-Dihydroxypregna-1,4,16-triene-3,20-dione 21-acetate, Pregna-1,4,16-triene-3,20-dione, 21-(acetyloxy)-11-hydroxy-, (11beta)-, (11b)-21-(Acetyloxy)-11-hydroxypregna-1,4,16-triene-3,20-dione, 21-Acetoxy-11b-hydroxypregna-1,4,16-triene-3,20-dione, 21-acetoxy-11bhydroxypregna-1,4,16-triene-3,20-dione, 11-Hydroxy-3,20-dioxopregna-1,4,16-trien-21-yl acetate, 11beta-Hydroxy-3,20-dioxopregna-1,4,16-trien-21-yl acetate, 21-Acetoxy-11, A-hydroxyl-1,4,16-pregnatriene-3,20-dione, 21-acetoxy-11beta-hydroxy-1,4,16-pregnatriene-3,20-dione, 21-acetoxy-11beta-hydroxyl-1,4,16-pregnatriene-3,20-dione, (11

Safety & hazard information (GHS)

Health hazard

Signal word: Warning

Hazard statements

H361Suspected of damaging fertility or the unborn child
H412Harmful to aquatic life with long lasting effects

Precautionary statements: P203, P273, P280, P318, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 21-Acetoxy-11beta -hydroxypregna-1,4,16-triene-3,20-dione?

The CAS Registry Number of 21-Acetoxy-11beta -hydroxypregna-1,4,16-triene-3,20-dione is 3044-42-6. It is also known as 11beta,21-Dihydroxypregna-1,4,16-triene-3,20-dione 21-acetate, Pregna-1,4,16-triene-3,20-dione, 21-(acetyloxy)-11-hydroxy-, (11beta)-, (11b)-21-(Acetyloxy)-11-hydroxypregna-1,4,16-triene-3,20-dione.

What is the molecular formula and molecular weight of 21-Acetoxy-11beta -hydroxypregna-1,4,16-triene-3,20-dione?

21-Acetoxy-11beta -hydroxypregna-1,4,16-triene-3,20-dione has the molecular formula C23H28O5 and a molecular weight of 384.5 g/mol. Its IUPAC name is [2-[(8S,9S,10R,11S,13S,14S)-11-hydroxy-10,13-dimethyl-3-oxo-6,7,8,9,11,12,14,15-octahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethyl] acetate.

What is 21-Acetoxy-11beta -hydroxypregna-1,4,16-triene-3,20-dione used for?

21-Acetoxy-11beta -hydroxypregna-1,4,16-triene-3,20-dione is supplied as a characterised reference material related to Budesonide. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 21-Acetoxy-11beta -hydroxypregna-1,4,16-triene-3,20-dione can I order?

We supply 21-Acetoxy-11beta -hydroxypregna-1,4,16-triene-3,20-dione in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 21-Acetoxy-11beta -hydroxypregna-1,4,16-triene-3,20-dione?

Yes. Every lot of 21-Acetoxy-11beta -hydroxypregna-1,4,16-triene-3,20-dione is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 21-Acetoxy-11beta -hydroxypregna-1,4,16-triene-3,20-dione be shipped internationally?

Yes. 21-Acetoxy-11beta -hydroxypregna-1,4,16-triene-3,20-dione is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.