Doxifluridine

Name: Doxifluridine
Brand: Vaqora Chemicals
SKU: VQ-024752

About Doxifluridine

Doxifluridine (CAS 3094-09-5) is an impurity of Capecitabine offered by Vaqora Chemicals. With the molecular formula C9H11FN2O5, it has a molar mass of 246.19 g/mol. The IUPAC name is 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-methyloxolan-2-yl]-5-fluoropyrimidine-2,4-dione. Alternative names: 5'-Deoxy-5-fluorouridine and 5-fluoro-5'-deoxyuridine.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. The GHS classification uses the signal word “Danger”, so appropriate gloves, eye protection and ventilation are recommended.

As a characterised impurity of Capecitabine, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

We offer Doxifluridine in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Capecitabine

View every impurity, metabolite and intermediate we list for Capecitabine.

Capecitabine impurities

Specifications & identifiers

Chemical identifiers
Product name	Doxifluridine
Catalogue No.	VQ-024752
CAS Number	3094-09-5
IUPAC name	1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-methyloxolan-2-yl]-5-fluoropyrimidine-2,4-dione
Molecular formula	C₉H₁₁FN₂O₅
Molecular weight	246.19 g/mol
Exact mass	246.0652
Grade	Reference Standard
HSN code	38229090
InChIKey	ZWAOHEXOSAUJHY-ZIYNGMLESA-N
SMILES	C[C@@H]1[C@H]([C@H]([C@@H](O1)N2C=C(C(=O)NC2=O)F)O)O
PubChem CID	18343

Physical properties
Physical form	Solid
LogP (XLogP3)	-1.7
H-bond donors / acceptors	3 / 6
TPSA	99.1 Å²
Synonyms	5'-Deoxy-5-fluorouridine, 5-fluoro-5'-deoxyuridine, Uridine, 5'-deoxy-5-fluoro-, 5'-Dfur, Uridine-5'-deoxy-5-fluoro-, 1-(beta-D-5-Desoxyribofuranoxyl)-5-fluoruracil, 5-DFUR, doxyfluridine, 5'-fluoro-5'-deoxyuridine, 5'-deoxy-5'-fluorouridine, 5'-dFUrd, 5'dFUrd

Safety & hazard information (GHS)

Flammable

Harmful / irritant

Health hazard

Environmental hazard

Signal word: Danger

Hazard statements

H226Flammable liquid and vapor
H315Causes skin irritation
H317May cause an allergic skin reaction
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation
H340May cause genetic defects
H350May cause cancer
H351Suspected of causing cancer
H360May damage fertility or the unborn child
H411Toxic to aquatic life with long lasting effects

Precautionary statements: P203, P210, P233, P240, P241, P242, P243, P261, P264, P264 + P265, P271, P272, P273, P280, P302 + P352, P303 + P361 + P353, P304 + P340, P305 + P351 + P338, P317, P318, P319, P321, P332 + P317, P333 + P317

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Doxifluridine?

The CAS Registry Number of Doxifluridine is 3094-09-5. It is also known as 5'-Deoxy-5-fluorouridine, 5-fluoro-5'-deoxyuridine, Uridine, 5'-deoxy-5-fluoro-.

What is the molecular formula and molecular weight of Doxifluridine?

Doxifluridine has the molecular formula C9H11FN2O5 and a molecular weight of 246.19 g/mol. Its IUPAC name is 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-methyloxolan-2-yl]-5-fluoropyrimidine-2,4-dione.

What is Doxifluridine used for?

Doxifluridine is supplied as a characterised reference material related to Capecitabine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Doxifluridine can I order?

We supply Doxifluridine in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Doxifluridine?

Yes. Every lot of Doxifluridine is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Doxifluridine be shipped internationally?

Yes. Doxifluridine is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.