6-Chloro-1-methyluracil

Name: 6-Chloro-1-methyluracil
Brand: Vaqora Chemicals
SKU: VQ-047367

About 6-Chloro-1-methyluracil

6-Chloro-1-methyluracil (CAS 31737-09-4) is a process intermediate or related compound of Alogliptin benzoate offered by Vaqora Chemicals. Its molecular formula is C5H5ClN2O2 and its molecular weight is 160.56 g/mol. Systematically, it is named 6-chloro-1-methylpyrimidine-2,4-dione. It is also known as Uracil, 6-chloro-1-methyl- or 1-methyl-6-chlorouracil.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. It carries the GHS signal word “Warning” with 4 hazard statements. Review the Safety Data Sheet before use.

Process chemists and analysts use it when developing synthetic routes to Alogliptin benzoate, tracking process-related impurities and validating analytical methods. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, 6-Chloro-1-methyluracil is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

API route development
Impurity fate & purge studies
Analytical method development

Industries

Related to Alogliptin benzoate

View every impurity, metabolite and intermediate we list for Alogliptin benzoate.

Alogliptin benzoate impurities

Specifications & identifiers

Chemical identifiers
Product name	6-Chloro-1-methyluracil
Catalogue No.	VQ-047367
CAS Number	31737-09-4
IUPAC name	6-chloro-1-methylpyrimidine-2,4-dione
Molecular formula	C₅H₅ClN₂O₂
Molecular weight	160.56 g/mol
Exact mass	160.004
HSN code	2933
InChIKey	AOSGEKKSRYJBGW-UHFFFAOYSA-N
SMILES	CN1C(=CC(=O)NC1=O)Cl
PubChem CID	3015589

Physical properties
Physical form	Solid
H-bond donors / acceptors	1 / 2
TPSA	49.4 Å²
Synonyms	Uracil, 6-chloro-1-methyl-, 6-chloro-1-methyl-1,2,3,4-tetrahydropyrimidine-2,4-dione, 6-Chloro-4-hydroxy-1-methylpyrimidin-2(1H)-one, 2,4(1H,3H)-Pyrimidinedione, 6-chloro-1-methyl-, 1-methyl-6-chlorouracil, 6-chloro-1-methyl-2,4(1H,3H)-pyrimidinedione, 6-chloro-1-methyl-pyrimidine-2,4-dione

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 6-Chloro-1-methyluracil?

The CAS Registry Number of 6-Chloro-1-methyluracil is 31737-09-4. It is also known as Uracil, 6-chloro-1-methyl-, 6-chloro-1-methyl-1,2,3,4-tetrahydropyrimidine-2,4-dione, 6-Chloro-4-hydroxy-1-methylpyrimidin-2(1H)-one.

What is the molecular formula and molecular weight of 6-Chloro-1-methyluracil?

6-Chloro-1-methyluracil has the molecular formula C5H5ClN2O2 and a molecular weight of 160.56 g/mol. Its IUPAC name is 6-chloro-1-methylpyrimidine-2,4-dione.

What is 6-Chloro-1-methyluracil used for?

6-Chloro-1-methyluracil is supplied as a characterised reference material related to Alogliptin benzoate. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 6-Chloro-1-methyluracil can I order?

We supply 6-Chloro-1-methyluracil, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 6-Chloro-1-methyluracil?

Yes. Every lot of 6-Chloro-1-methyluracil is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 6-Chloro-1-methyluracil be shipped internationally?

Yes. 6-Chloro-1-methyluracil is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.