N4-Hydroxycytidine

About N4-Hydroxycytidine

N4-Hydroxycytidine is a process intermediate or related compound of Molnupiravir carrying the CAS registry number 3258-02-4. Its molecular formula is C9H13N3O6 and its molecular weight is 259.22 g/mol. Systematically, it is named 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-4-(hydroxyamino)pyrimidin-2-one. Alternative names: EIDD 1931 and N-Hydroxycytidine.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. It carries the GHS signal word “Warning” with 4 hazard statements. Review the Safety Data Sheet before use.

It is a process intermediate or related compound in the synthesis of Molnupiravir, useful for route development, impurity fate-and-purge studies and analytical method development. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

We offer N4-Hydroxycytidine in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide. This item is currently in stock for prompt dispatch.

Typical applications

API route development
Impurity fate & purge studies
Analytical method development

Industries

Related to Molnupiravir

View every impurity, metabolite and intermediate we list for Molnupiravir.

Molnupiravir impurities

Specifications & identifiers

Chemical identifiers
Product name	N4-Hydroxycytidine
Catalogue No.	VQ-013653
CAS Number	3258-02-4
IUPAC name	1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-4-(hydroxyamino)pyrimidin-2-one
Molecular formula	C₉H₁₃N₃O₆
Molecular weight	259.22 g/mol
Exact mass	259.0804
Grade	Reference Standard
HSN code	2933
InChIKey	XCUAIINAJCDIPM-XVFCMESISA-N
SMILES	C1=CN(C(=O)N=C1NO)[C@H]2[C@@H]([C@@H]([C@H](O2)CO)O)O
PubChem CID	197020

Physical properties
Physical form	Solid
LogP (XLogP3)	-2.2
H-bond donors / acceptors	5 / 6
TPSA	135 Å²
Synonyms	EIDD 1931, N-Hydroxycytidine, NHC, 4-Oxime Uridine, N(4)-Hydroxycytidine, EIDD-1931, Uridine, 4-oxime, 4-N-Hydroxycytidine, EiDD1931, Beta-D-N4-hydroxycytidine, N-4-Hydroxycytidine, Cytidine, N-hydroxy-

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of N4-Hydroxycytidine?

The CAS Registry Number of N4-Hydroxycytidine is 3258-02-4. It is also known as EIDD 1931, N-Hydroxycytidine, NHC.

What is the molecular formula and molecular weight of N4-Hydroxycytidine?

N4-Hydroxycytidine has the molecular formula C9H13N3O6 and a molecular weight of 259.22 g/mol. Its IUPAC name is 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-4-(hydroxyamino)pyrimidin-2-one.

What is N4-Hydroxycytidine used for?

N4-Hydroxycytidine is supplied as a characterised reference material related to Molnupiravir. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of N4-Hydroxycytidine can I order?

We supply N4-Hydroxycytidine in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with N4-Hydroxycytidine?

Yes. Every lot of N4-Hydroxycytidine is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can N4-Hydroxycytidine be shipped internationally?

Yes. N4-Hydroxycytidine is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.