(3AR,5aR,8aR,8bS)-3a-(Chloromethyl)-2,2,7,7-t… 32785-90-3

Name: (3AR,5aR,8aR,8bS)-3a-(Chloromethyl)-2,2,7,7-tetramethyltetrahydro-5H-bis([1,3]dioxolo)[4,5-b:4',5'-d]pyran
Brand: Vaqora Chemicals
SKU: VQ-028461

About (3AR,5aR,8aR,8bS)-3a-(Chloromethyl)-2,2,7,7-tetramethyltetrahydro-5H-bis([1,3]dioxolo)[4,5-b:4',5'-d]pyran

(3AR,5aR,8aR,8bS)-3a-(Chloromethyl)-2,2,7,7-tetramethyltetrahydro-5H-bis([1,3]dioxolo)[4,5-b:4',5'-d]pyran (CAS 32785-90-3) is an impurity of Topiramate offered by Vaqora Chemicals. With the molecular formula C12H19ClO5, it has a molar mass of 278.73 g/mol. Its systematic (IUPAC) name is (1R,2S,6R,9R)-6-(chloromethyl)-4,4,11,11-tetramethyl-3,5,7,10,12-pentaoxatricyclo[7.3.0.02,6]dodecane. Alternative names: D-Fructopiranose Hydrochloride.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

Pharmaceutical QC and development laboratories use this impurity standard of Topiramate to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. It is used across pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Topiramate

View every impurity, metabolite and intermediate we list for Topiramate.

Topiramate impurities

Specifications & identifiers

Chemical identifiers
Product name	(3AR,5aR,8aR,8bS)-3a-(Chloromethyl)-2,2,7,7-tetramethyltetrahydro-5H-bis([1,3]dioxolo)[4,5-b:4',5'-d]pyran
Catalogue No.	VQ-028461
CAS Number	32785-90-3
IUPAC name	(1R,2S,6R,9R)-6-(chloromethyl)-4,4,11,11-tetramethyl-3,5,7,10,12-pentaoxatricyclo[7.3.0.02,6]dodecane
Molecular formula	C₁₂H₁₉ClO₅
Molecular weight	278.73 g/mol
Exact mass	278.0921
Grade	Reference Standard
HSN code	38229090
InChIKey	JPOKXWDHLOMNQX-XBWDGYHZSA-N
SMILES	CC1(O[C@@H]2CO[C@@]3([C@H]([C@@H]2O1)OC(O3)(C)C)CCl)C
PubChem CID	168450788

Physical properties
Physical form	Solid
LogP (XLogP3)	1
H-bond donors / acceptors	0 / 5
TPSA	46.2 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of (3AR,5aR,8aR,8bS)-3a-(Chloromethyl)-2,2,7,7-tetramethyltetrahydro-5H-bis([1,3]dioxolo)[4,5-b:4',5'-d]pyran?

The CAS Registry Number of (3AR,5aR,8aR,8bS)-3a-(Chloromethyl)-2,2,7,7-tetramethyltetrahydro-5H-bis([1,3]dioxolo)[4,5-b:4',5'-d]pyran is 32785-90-3. It is also known as D-Fructopiranose Hydrochloride.

What is the molecular formula and molecular weight of (3AR,5aR,8aR,8bS)-3a-(Chloromethyl)-2,2,7,7-tetramethyltetrahydro-5H-bis([1,3]dioxolo)[4,5-b:4',5'-d]pyran?

(3AR,5aR,8aR,8bS)-3a-(Chloromethyl)-2,2,7,7-tetramethyltetrahydro-5H-bis([1,3]dioxolo)[4,5-b:4',5'-d]pyran has the molecular formula C12H19ClO5 and a molecular weight of 278.73 g/mol. Its IUPAC name is (1R,2S,6R,9R)-6-(chloromethyl)-4,4,11,11-tetramethyl-3,5,7,10,12-pentaoxatricyclo[7.3.0.02,6]dodecane.

What is (3AR,5aR,8aR,8bS)-3a-(Chloromethyl)-2,2,7,7-tetramethyltetrahydro-5H-bis([1,3]dioxolo)[4,5-b:4',5'-d]pyran used for?

(3AR,5aR,8aR,8bS)-3a-(Chloromethyl)-2,2,7,7-tetramethyltetrahydro-5H-bis([1,3]dioxolo)[4,5-b:4',5'-d]pyran is supplied as a characterised reference material related to Topiramate. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of (3AR,5aR,8aR,8bS)-3a-(Chloromethyl)-2,2,7,7-tetramethyltetrahydro-5H-bis([1,3]dioxolo)[4,5-b:4',5'-d]pyran can I order?

We supply (3AR,5aR,8aR,8bS)-3a-(Chloromethyl)-2,2,7,7-tetramethyltetrahydro-5H-bis([1,3]dioxolo)[4,5-b:4',5'-d]pyran in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with (3AR,5aR,8aR,8bS)-3a-(Chloromethyl)-2,2,7,7-tetramethyltetrahydro-5H-bis([1,3]dioxolo)[4,5-b:4',5'-d]pyran?

Yes. Every lot of (3AR,5aR,8aR,8bS)-3a-(Chloromethyl)-2,2,7,7-tetramethyltetrahydro-5H-bis([1,3]dioxolo)[4,5-b:4',5'-d]pyran is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can (3AR,5aR,8aR,8bS)-3a-(Chloromethyl)-2,2,7,7-tetramethyltetrahydro-5H-bis([1,3]dioxolo)[4,5-b:4',5'-d]pyran be shipped internationally?

Yes. We export (3AR,5aR,8aR,8bS)-3a-(Chloromethyl)-2,2,7,7-tetramethyltetrahydro-5H-bis([1,3]dioxolo)[4,5-b:4',5'-d]pyran worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.