Quetiapine Impurity S

About Quetiapine Impurity S

Quetiapine Impurity S is an impurity of Quetiapine carrying the CAS registry number 329216-63-9. With the molecular formula C21H25N3O3S, it has a molar mass of 399.5 g/mol. The IUPAC name is 2-[2-[4-[(11S)-11-oxobenzo[b][1,4]benzothiazepin-6-yl]piperazin-1-yl]ethoxy]ethanol. It is also known as Quetiapine S-Oxide or Quetiapine Sulfoxide.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. It carries the GHS signal word “Warning” with 1 hazard statement. Review the Safety Data Sheet before use.

Pharmaceutical QC and development laboratories use this impurity standard of Quetiapine to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Quetiapine

View every impurity, metabolite and intermediate we list for Quetiapine.

Quetiapine impurities

Specifications & identifiers

Chemical identifiers
Product name	Quetiapine Impurity S
Catalogue No.	VQ-005672
CAS Number	329216-63-9
Other CAS	2448341-72-6, 329218-11-3
IUPAC name	2-[2-[4-[(11S)-11-oxobenzo[b][1,4]benzothiazepin-6-yl]piperazin-1-yl]ethoxy]ethanol
Molecular formula	C₂₁H₂₅N₃O₃S
Molecular weight	399.5 g/mol
Exact mass	399.1617
Grade	Reference Standard
HSN code	38229090
InChIKey	FXJNLPUSSHEDON-NDEPHWFRSA-N
SMILES	C1CN(CCN1CCOCCO)C2=NC3=CC=CC=C3[S@@](=O)C4=CC=CC=C42
PubChem CID	10431050

Physical properties
Physical form	Solid
LogP (XLogP3)	0.9
H-bond donors / acceptors	1 / 7
TPSA	94.1 Å²
Synonyms	2-[2-[4-(5-Oxidodibenzo[b,f][1,4]thiazepin-11-yl)-1-piperazinyl]ethoxy]ethanol, Quetiapine S-Oxide, Quetiapine Sulfoxide, Ethanol, 2-[2-[4-(5-oxidodibenzo[b,f][1,4]thiazepin-11-yl)-1-piperazinyl]ethoxy]-, 2-(2-(4-(5-Oxidodibenzo(b,f)(1,4)thiazepin-11-yl)piperazin-1-yl)ethoxy)ethanol, Ethanol, 2-(2-(4-(5-oxidodibenzo(b,f)(1,4)thiazepin-11-yl)-1-piperazinyl)ethoxy)-, Quetiapine fumarate impurity S, Quetiapine EP Impurity S, 2-[2-[4-(11-oxobenzo[b][1,4]benzothiazepin-6-yl)piperazin-1-yl]ethoxy]ethanol, QuetiapineSulfoxide, Quetiapine-sulfoxide, Quetiapine metabolite Quetiapine sulfoxide

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements: P264, P270, P301 + P317, P330, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Quetiapine Impurity S?

The CAS Registry Number of Quetiapine Impurity S is 329216-63-9. It is also known as 2-[2-[4-(5-Oxidodibenzo[b,f][1,4]thiazepin-11-yl)-1-piperazinyl]ethoxy]ethanol, Quetiapine S-Oxide, Quetiapine Sulfoxide.

What is the molecular formula and molecular weight of Quetiapine Impurity S?

Quetiapine Impurity S has the molecular formula C21H25N3O3S and a molecular weight of 399.5 g/mol. Its IUPAC name is 2-[2-[4-[(11S)-11-oxobenzo[b][1,4]benzothiazepin-6-yl]piperazin-1-yl]ethoxy]ethanol.

What is Quetiapine Impurity S used for?

Quetiapine Impurity S is supplied as a characterised reference material related to Quetiapine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Quetiapine Impurity S can I order?

We supply Quetiapine Impurity S in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Quetiapine Impurity S?

Yes. Every lot of Quetiapine Impurity S is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Quetiapine Impurity S be shipped internationally?

Yes. Quetiapine Impurity S is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.