Nicarbazine

About Nicarbazine

Nicarbazine is a high-purity reference standard of Nicarbazin carrying the CAS registry number 330-95-0. Its molecular formula is C19H18N6O6 and its molecular weight is 426.4 g/mol. It is also known as Nicarbazin or Nirazin.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

Laboratories use this Nicarbazin standard for identity and assay testing, system suitability checks and method validation supporting ANDA and DMF filings. It is used across pharmaceutical manufacturing and academic and industrial research.

We offer Nicarbazine in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Nicarbazin

View every impurity, metabolite and intermediate we list for Nicarbazin.

Nicarbazin impurities

Specifications & identifiers

Chemical identifiers
Product name	Nicarbazine
Catalogue No.	VQ-027090
CAS Number	330-95-0
IUPAC name	1,3-bis(4-nitrophenyl)urea;4,6-dimethyl-1H-pyrimidin-2-one
Molecular formula	C₁₉H₁₈N₆O₆
Molecular weight	426.4 g/mol
Exact mass	426.1288
Grade	Reference Standard
HSN code	38229090
InChIKey	UKHWDRMMMYWSFL-UHFFFAOYSA-N
SMILES	CC1=CC(=NC(=O)N1)C.C1=CC(=CC=C1NC(=O)NC2=CC=C(C=C2)[N+](=O)[O-])[N+](=O)[O-]
PubChem CID	9507

Physical properties
Physical form	Solid
H-bond donors / acceptors	3 / 6
TPSA	174 Å²
Synonyms	Nicarbazin, Nirazin, Nicoxin, Nicrazin, Nicrazine, Nicarbasin, MK 75, Nicarmix 25, Carbigran 25, Nicarbazin, 1,3-Bis(4-nitrophenyl)urea 4,6-dimethylpyrimidin-2-ol (1:1), n,n'-bis(4-nitrophenyl)urea compound with 4,6-dimethyl-2-pyrimidinone, MK 75 (VAN)

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P271, P280, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Nicarbazine?

The CAS Registry Number of Nicarbazine is 330-95-0. It is also known as Nicarbazin, Nirazin, Nicoxin.

What is the molecular formula and molecular weight of Nicarbazine?

Nicarbazine has the molecular formula C19H18N6O6 and a molecular weight of 426.4 g/mol.

What is Nicarbazine used for?

Nicarbazine is supplied as a characterised reference material related to Nicarbazin. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Nicarbazine can I order?

We supply Nicarbazine in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Nicarbazine?

Yes. Every lot of Nicarbazine is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Nicarbazine be shipped internationally?

Yes. Nicarbazine is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.