Lubiprostone Hemiketal

Name: Lubiprostone Hemiketal
Brand: Vaqora Chemicals
SKU: VQ-048973

About Lubiprostone Hemiketal

Lubiprostone Hemiketal (CAS 333963-40-9) is a process intermediate or related compound of Lubiprostone offered by Vaqora Chemicals. Its molecular formula is C20H32F2O5 and its molecular weight is 390.5 g/mol. It is also known as Lubiprostone or SPI-0211.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Good laboratory practice and suitable PPE are recommended during handling.

It is a process intermediate or related compound in the synthesis of Lubiprostone, useful for route development, impurity fate-and-purge studies and analytical method development. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Lubiprostone Hemiketal in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

API route development
Impurity fate & purge studies
Analytical method development

Industries

Related to Lubiprostone

View every impurity, metabolite and intermediate we list for Lubiprostone.

Lubiprostone impurities

Specifications & identifiers

Chemical identifiers
Product name	Lubiprostone Hemiketal
Catalogue No.	VQ-048973
CAS Number	333963-40-9
IUPAC name	7-[(2R,4aR,5R,7aR)-2-(1,1-difluoropentyl)-2-hydroxy-6-oxo-3,4,4a,5,7,7a-hexahydrocyclopenta[b]pyran-5-yl]heptanoic acid
Molecular formula	C₂₀H₃₂F₂O₅
Molecular weight	390.5 g/mol
Exact mass	390.2218
InChIKey	WGFOBBZOWHGYQH-MXHNKVEKSA-N
SMILES	CCCCC([C@]1(CC[C@H]2[C@H](O1)CC(=O)[C@@H]2CCCCCCC(=O)O)O)(F)F
PubChem CID	157920

Physical properties
Physical form	Solid
LogP (XLogP3)	4
H-bond donors / acceptors	2 / 7
TPSA	83.8 Å²
Synonyms	Lubiprostone, SPI-0211, Prostan-1-oic acid, 11,15-epoxy-16,16-difluoro-15-hydroxy-9-oxo-, (11alpha,15R)-, 0211, SPI, 0211, RU, Prostan-1-oic acid, 16,16-difluoro-11-hydroxy-9,15-dioxo-, (11alpha)-, Bicyclic lubiprostone, Lubiprostone powder, Lubiprostone (ring open), EX-A1771

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Lubiprostone Hemiketal?

The CAS Registry Number of Lubiprostone Hemiketal is 333963-40-9. It is also known as Lubiprostone, SPI-0211, Prostan-1-oic acid, 11,15-epoxy-16,16-difluoro-15-hydroxy-9-oxo-, (11alpha,15R)-.

What is the molecular formula and molecular weight of Lubiprostone Hemiketal?

Lubiprostone Hemiketal has the molecular formula C20H32F2O5 and a molecular weight of 390.5 g/mol. Its IUPAC name is 7-[(2R,4aR,5R,7aR)-2-(1,1-difluoropentyl)-2-hydroxy-6-oxo-3,4,4a,5,7,7a-hexahydrocyclopenta[b]pyran-5-yl]heptanoic acid.

What is Lubiprostone Hemiketal used for?

Lubiprostone Hemiketal is supplied as a characterised reference material related to Lubiprostone. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Lubiprostone Hemiketal can I order?

We supply Lubiprostone Hemiketal, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Lubiprostone Hemiketal?

Yes. Every lot of Lubiprostone Hemiketal is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Lubiprostone Hemiketal be shipped internationally?

Yes. We export Lubiprostone Hemiketal worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.