5-Fluoropyrazin-2(1H)-one

About 5-Fluoropyrazin-2(1H)-one

5-Fluoropyrazin-2(1H)-one is an impurity of Favipiravir carrying the CAS registry number 33870-92-7. With the molecular formula C4H3FN2O, it has a molar mass of 114.08 g/mol. The IUPAC name is 5-fluoro-1H-pyrazin-2-one. It is also known as 5-fluoropyrazin-2-ol or 5-Fluoro-2(1H)-pyrazinone.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

This Favipiravir impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. It is used across pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Favipiravir

View every impurity, metabolite and intermediate we list for Favipiravir.

Favipiravir impurities

Specifications & identifiers

Chemical identifiers
Product name	5-Fluoropyrazin-2(1H)-one
Catalogue No.	VQ-035276
CAS Number	33870-92-7
IUPAC name	5-fluoro-1H-pyrazin-2-one
Molecular formula	C₄H₃FN₂O
Molecular weight	114.08 g/mol
Exact mass	114.0229
Grade	Reference Standard
HSN code	38229090
InChIKey	FQODCEGFPWHSGX-UHFFFAOYSA-N
SMILES	C1=C(N=CC(=O)N1)F
PubChem CID	71361084

Physical properties
Physical form	Solid
LogP (XLogP3)	-0.4
H-bond donors / acceptors	1 / 3
TPSA	41.5 Å²

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H312Harmful in contact with skin
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P317, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 5-Fluoropyrazin-2(1H)-one?

The CAS Registry Number of 5-Fluoropyrazin-2(1H)-one is 33870-92-7. It is also known as 5-fluoropyrazin-2-ol, 5-Fluoro-2(1H)-pyrazinone.

What is the molecular formula and molecular weight of 5-Fluoropyrazin-2(1H)-one?

5-Fluoropyrazin-2(1H)-one has the molecular formula C4H3FN2O and a molecular weight of 114.08 g/mol. Its IUPAC name is 5-fluoro-1H-pyrazin-2-one.

What is 5-Fluoropyrazin-2(1H)-one used for?

5-Fluoropyrazin-2(1H)-one is supplied as a characterised reference material related to Favipiravir. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 5-Fluoropyrazin-2(1H)-one can I order?

We supply 5-Fluoropyrazin-2(1H)-one in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 5-Fluoropyrazin-2(1H)-one?

Yes. Every lot of 5-Fluoropyrazin-2(1H)-one is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 5-Fluoropyrazin-2(1H)-one be shipped internationally?

Yes. 5-Fluoropyrazin-2(1H)-one is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.