Netupitant Impurity 24

About Netupitant Impurity 24

Netupitant Impurity 24 is an impurity of Netupitant carrying the CAS registry number 342417-01-0. Formula C18H22N4O, molecular weight 310.4 g/mol. Systematically, it is named 4-(2-methylphenyl)-6-(4-methylpiperazin-1-yl)pyridine-3-carboxamide. Alternative names: Netupitant ITS-1.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Good laboratory practice and suitable PPE are recommended during handling.

Pharmaceutical QC and development laboratories use this impurity standard of Netupitant to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

We offer Netupitant Impurity 24 in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Netupitant

View every impurity, metabolite and intermediate we list for Netupitant.

Netupitant impurities

Specifications & identifiers

Chemical identifiers
Product name	Netupitant Impurity 24
Catalogue No.	VQ-049219
CAS Number	342417-01-0
IUPAC name	4-(2-methylphenyl)-6-(4-methylpiperazin-1-yl)pyridine-3-carboxamide
Molecular formula	C₁₈H₂₂N₄O
Molecular weight	310.4 g/mol
Exact mass	310.1794
Grade	Reference Standard
HSN code	38229090
InChIKey	UQTDFKWGXOVHFZ-UHFFFAOYSA-N
SMILES	CC1=CC=CC=C1C2=CC(=NC=C2C(=O)N)N3CCN(CC3)C
PubChem CID	11483728

Physical properties
Physical form	Solid
LogP (XLogP3)	2
H-bond donors / acceptors	1 / 4
TPSA	62.5 Å²
Synonyms	6-(4-Methylpiperazin-1-yl)-4-O-tolylnicotinamide, 6-(4-methylpiperazin-1-yl)-4-(o-tolyl)nicotinamide, Netupitant ITS-1, 6-(4-Methylpiperazin-1-yl)-4-(2-methylphenyl)nicotinamide, 6-(4-Methyl-1-piperazinyl)-4-(o-tolyl)nicotinamide, 4-(2-methylphenyl)-6-(4-methylpiperazinyl)-3-pyridinecarboxamide, 6-(4-methylpiperazin-1-yl)-4-o-tolyl-nicotinamide, 6-(4-methyl-piperazin-1-yl)-4-o-tolyl-nicotinamide, 6-(4-methylpiperazin-1-yl)-4-(o-tolyl)pyridine-3-carboxamide

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Netupitant Impurity 24?

The CAS Registry Number of Netupitant Impurity 24 is 342417-01-0. It is also known as 6-(4-Methylpiperazin-1-yl)-4-O-tolylnicotinamide, 6-(4-methylpiperazin-1-yl)-4-(o-tolyl)nicotinamide, Netupitant ITS-1.

What is the molecular formula and molecular weight of Netupitant Impurity 24?

Netupitant Impurity 24 has the molecular formula C18H22N4O and a molecular weight of 310.4 g/mol. Its IUPAC name is 4-(2-methylphenyl)-6-(4-methylpiperazin-1-yl)pyridine-3-carboxamide.

What is Netupitant Impurity 24 used for?

Netupitant Impurity 24 is supplied as a characterised reference material related to Netupitant. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Netupitant Impurity 24 can I order?

We supply Netupitant Impurity 24 in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Netupitant Impurity 24?

Yes. Every lot of Netupitant Impurity 24 is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Netupitant Impurity 24 be shipped internationally?

Yes. We export Netupitant Impurity 24 worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.