Rel-(1R,3r,5S)-3-Hydroxyspiro[bicyclo[3.2.1]o… 3464-71-9

Name: Rel-(1R,3r,5S)-3-Hydroxyspiro[bicyclo[3.2.1]octane-8,1'-pyrrolidin]-8-ium chloride
Brand: Vaqora Chemicals
SKU: VQ-021356

About Rel-(1R,3r,5S)-3-Hydroxyspiro[bicyclo[3.2.1]octane-8,1'-pyrrolidin]-8-ium chloride

Vaqora Chemicals supplies Rel-(1R,3r,5S)-3-Hydroxyspiro[bicyclo[3.2.1]octane-8,1'-pyrrolidin]-8-ium chloride, an impurity of Trospium registered under CAS number 3464-71-9. Its molecular formula is C11H20ClNO and its molecular weight is 217.73 g/mol. Systematically, it is named (1R,5S)-spiro[8-azoniabicyclo[3.2.1]octane-8,1'-azolidin-1-ium]-3-ol chloride. Alternative names: Azoniaspironortropanol chloride and Trospium Alcohol Chloride.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. It carries the GHS signal word “Warning” with 4 hazard statements. Review the Safety Data Sheet before use.

As a characterised impurity of Trospium, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Rel-(1R,3r,5S)-3-Hydroxyspiro[bicyclo[3.2.1]octane-8,1'-pyrrolidin]-8-ium chloride in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Trospium

View every impurity, metabolite and intermediate we list for Trospium.

Trospium impurities

Specifications & identifiers

Chemical identifiers
Product name	Rel-(1R,3r,5S)-3-Hydroxyspiro[bicyclo[3.2.1]octane-8,1'-pyrrolidin]-8-ium chloride
Catalogue No.	VQ-021356
CAS Number	3464-71-9
IUPAC name	(1R,5S)-spiro[8-azoniabicyclo[3.2.1]octane-8,1'-azolidin-1-ium]-3-ol chloride
Molecular formula	C₁₁H₂₀ClNO
Molecular weight	217.73 g/mol
Exact mass	217.1233
Grade	Reference Standard
HSN code	38229090
InChIKey	HZDYZXDBRXHZIX-DIVWUKMWSA-M
SMILES	C1CC[N+]2(C1)[C@@H]3CC[C@H]2CC(C3)O.[Cl-]
PubChem CID	72941453

Physical properties
Physical form	Solid
H-bond donors / acceptors	1 / 2
TPSA	20.2 Å²
Synonyms	Azoniaspironortropanol chloride, (1R,3R,5S)-3-Hydroxyspiro(8-azoniabicyclo(3.2.1)octane-8,1'-pyrrolidinium) chloride, (1R,3r,5S)-3-Hydroxyspiro[8-azoniabicyclo[3.2.1]octane-8,1'-pyrrolidinium] Chloride, (1R,3r,5S)-3-hydroxyspiro[bicyclo[3.2.1]octane-8,1'-pyrrolidin]-8-ium chloride, Trospium Alcohol Chloride, 3I+/--Hydroxynortropane-8-spiro-1'-pyrrolidinium chloride, endo-3-Hydroxyspiro[bicyclo[3.2.1]octane-8,1'-pyrrolidin]-1'-ium Chloride

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302+H332Harmful if swallowed or if inhaled
H302Harmful if swallowed
H332Harmful if inhaled
H412Harmful to aquatic life with long lasting effects

Precautionary statements: P261, P264, P270, P271, P273, P301 + P317, P304 + P340, P317, P330, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Rel-(1R,3r,5S)-3-Hydroxyspiro[bicyclo[3.2.1]octane-8,1'-pyrrolidin]-8-ium chloride?

The CAS Registry Number of Rel-(1R,3r,5S)-3-Hydroxyspiro[bicyclo[3.2.1]octane-8,1'-pyrrolidin]-8-ium chloride is 3464-71-9. It is also known as Azoniaspironortropanol chloride, (1R,3R,5S)-3-Hydroxyspiro(8-azoniabicyclo(3.2.1)octane-8,1'-pyrrolidinium) chloride, (1R,3r,5S)-3-Hydroxyspiro[8-azoniabicyclo[3.2.1]octane-8,1'-pyrrolidinium] Chloride.

What is the molecular formula and molecular weight of Rel-(1R,3r,5S)-3-Hydroxyspiro[bicyclo[3.2.1]octane-8,1'-pyrrolidin]-8-ium chloride?

Rel-(1R,3r,5S)-3-Hydroxyspiro[bicyclo[3.2.1]octane-8,1'-pyrrolidin]-8-ium chloride has the molecular formula C11H20ClNO and a molecular weight of 217.73 g/mol. Its IUPAC name is (1R,5S)-spiro[8-azoniabicyclo[3.2.1]octane-8,1'-azolidin-1-ium]-3-ol chloride.

What is Rel-(1R,3r,5S)-3-Hydroxyspiro[bicyclo[3.2.1]octane-8,1'-pyrrolidin]-8-ium chloride used for?

Rel-(1R,3r,5S)-3-Hydroxyspiro[bicyclo[3.2.1]octane-8,1'-pyrrolidin]-8-ium chloride is supplied as a characterised reference material related to Trospium. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Rel-(1R,3r,5S)-3-Hydroxyspiro[bicyclo[3.2.1]octane-8,1'-pyrrolidin]-8-ium chloride can I order?

We supply Rel-(1R,3r,5S)-3-Hydroxyspiro[bicyclo[3.2.1]octane-8,1'-pyrrolidin]-8-ium chloride in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Rel-(1R,3r,5S)-3-Hydroxyspiro[bicyclo[3.2.1]octane-8,1'-pyrrolidin]-8-ium chloride?

Yes. Every lot of Rel-(1R,3r,5S)-3-Hydroxyspiro[bicyclo[3.2.1]octane-8,1'-pyrrolidin]-8-ium chloride is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Rel-(1R,3r,5S)-3-Hydroxyspiro[bicyclo[3.2.1]octane-8,1'-pyrrolidin]-8-ium chloride be shipped internationally?

Yes. Rel-(1R,3r,5S)-3-Hydroxyspiro[bicyclo[3.2.1]octane-8,1'-pyrrolidin]-8-ium chloride is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.