4-Chloro-2-nitrobenzonitrile

About 4-Chloro-2-nitrobenzonitrile

4-Chloro-2-nitrobenzonitrile is a process intermediate or related compound of Alectinib carrying the CAS registry number 34662-32-3. The compound has the formula C7H3ClN2O2, corresponding to a molecular weight of 182.56 g/mol. It is also known as Benzonitrile, 4-chloro-2-nitro- or 2-Nitro-4-chlorobenzonitrile.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

Process chemists and analysts use it when developing synthetic routes to Alectinib, tracking process-related impurities and validating analytical methods. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

API route development
Impurity fate & purge studies
Analytical method development

Industries

Related to Alectinib

View every impurity, metabolite and intermediate we list for Alectinib.

Alectinib impurities

Specifications & identifiers

Chemical identifiers
Product name	4-Chloro-2-nitrobenzonitrile
Catalogue No.	VQ-051758
CAS Number	34662-32-3
IUPAC name	4-chloro-2-nitrobenzonitrile
Molecular formula	C₇H₃ClN₂O₂
Molecular weight	182.56 g/mol
Exact mass	181.9883
HSN code	2933
InChIKey	OZKOAADVLVCNFO-UHFFFAOYSA-N
SMILES	C1=CC(=C(C=C1Cl)[N+](=O)[O-])C#N
PubChem CID	96924

Physical properties
Physical form	Solid
LogP (XLogP3)	2
H-bond donors / acceptors	0 / 3
TPSA	69.6 Å²

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P271, P280, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 4-Chloro-2-nitrobenzonitrile?

The CAS Registry Number of 4-Chloro-2-nitrobenzonitrile is 34662-32-3. It is also known as Benzonitrile, 4-chloro-2-nitro-, 2-Nitro-4-chlorobenzonitrile, 4-chloro-2-nitrobenzenecarbonitrile.

What is the molecular formula and molecular weight of 4-Chloro-2-nitrobenzonitrile?

4-Chloro-2-nitrobenzonitrile has the molecular formula C7H3ClN2O2 and a molecular weight of 182.56 g/mol. Its IUPAC name is 4-chloro-2-nitrobenzonitrile.

What is 4-Chloro-2-nitrobenzonitrile used for?

4-Chloro-2-nitrobenzonitrile is supplied as a characterised reference material related to Alectinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 4-Chloro-2-nitrobenzonitrile can I order?

We supply 4-Chloro-2-nitrobenzonitrile, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 4-Chloro-2-nitrobenzonitrile?

Yes. Every lot of 4-Chloro-2-nitrobenzonitrile is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 4-Chloro-2-nitrobenzonitrile be shipped internationally?

Yes. 4-Chloro-2-nitrobenzonitrile is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.