4-chloro-5-fluoropyrimidine
Synonyms: 4-Chloro-5-fluoro-1,3-diazine · 4-chloro-5-fluoro-Pyrimidine · Pyrimidine, 4-chloro-5-fluoro- (9CI) · Pyrimidine,4-chloro-5-fluoro-
4-chloro-5-fluoropyrimidine (CAS 347418-42-2) – Voriconazole intermediate. C4H2ClFN2, MW 132.52. Buy from Vaqora Chemicals with COA and worldwide shipping.
About 4-chloro-5-fluoropyrimidine
4-chloro-5-fluoropyrimidine is a process intermediate or related compound of Voriconazole carrying the CAS registry number 347418-42-2. With the molecular formula C4H2ClFN2, it has a molar mass of 132.52 g/mol. Alternative names: 4-Chloro-5-fluoro-1,3-diazine and 4-chloro-5-fluoro-Pyrimidine.
The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. It carries the GHS signal word “Warning” with 7 hazard statements. Review the Safety Data Sheet before use.
Process chemists and analysts use it when developing synthetic routes to Voriconazole, tracking process-related impurities and validating analytical methods. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.
We offer 4-chloro-5-fluoropyrimidine in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide. This item is currently in stock for prompt dispatch.
Typical applications
- API route development
- Impurity fate & purge studies
- Analytical method development
Industries
View every impurity, metabolite and intermediate we list for Voriconazole.
Voriconazole impuritiesSpecifications & identifiers
| Product name | 4-chloro-5-fluoropyrimidine |
|---|---|
| Catalogue No. | VQ-013095 |
| CAS Number | 347418-42-2 |
| IUPAC name | 4-chloro-5-fluoropyrimidine |
| Molecular formula | C4H2ClFN2 |
| Molecular weight | 132.52 g/mol |
| Exact mass | 131.9891 |
| Grade | Reference Standard |
| HSN code | 2933 |
| InChIKey | APSSAJKZELMQNM-UHFFFAOYSA-N |
| SMILES | C1=C(C(=NC=N1)Cl)F |
| PubChem CID | 17893713 |
| Physical form | Solid |
|---|---|
| LogP (XLogP3) | 1.3 |
| H-bond donors / acceptors | 0 / 3 |
| TPSA | 25.8 Ų |
| Synonyms | 4-Chloro-5-fluoro-1,3-diazine, 4-chloro-5-fluoro-Pyrimidine, Pyrimidine, 4-chloro-5-fluoro- (9CI), Pyrimidine,4-chloro-5-fluoro-, Chloro-5-fluo, Chloro-5-fluoropyrimidine |
Safety & hazard information (GHS)
Signal word: Warning
Hazard statements
H227Combustible liquidH302Harmful if swallowedH312Harmful in contact with skinH315Causes skin irritationH319Causes serious eye irritationH332Harmful if inhaledH335May cause respiratory irritation
Precautionary statements: P210, P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P317, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P370 + P378, P403, P403 + P233, P405, P501
Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.
Documents
Frequently asked questions
What is the CAS number of 4-chloro-5-fluoropyrimidine?
The CAS Registry Number of 4-chloro-5-fluoropyrimidine is 347418-42-2. It is also known as 4-Chloro-5-fluoro-1,3-diazine, 4-chloro-5-fluoro-Pyrimidine, Pyrimidine, 4-chloro-5-fluoro- (9CI).
What is the molecular formula and molecular weight of 4-chloro-5-fluoropyrimidine?
4-chloro-5-fluoropyrimidine has the molecular formula C4H2ClFN2 and a molecular weight of 132.52 g/mol. Its IUPAC name is 4-chloro-5-fluoropyrimidine.
What is 4-chloro-5-fluoropyrimidine used for?
4-chloro-5-fluoropyrimidine is supplied as a characterised reference material related to Voriconazole. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.
Which grade and pack sizes of 4-chloro-5-fluoropyrimidine can I order?
We supply 4-chloro-5-fluoropyrimidine in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg packs. Larger bulk quantities and custom packing are quoted on request.
Do you provide a COA and SDS with 4-chloro-5-fluoropyrimidine?
Yes. Every lot of 4-chloro-5-fluoropyrimidine is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.
Can 4-chloro-5-fluoropyrimidine be shipped internationally?
Yes. 4-chloro-5-fluoropyrimidine is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.
Enquire about 4-chloro-5-fluoropyrimidine
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