trans-3-Hydroxy Cotinine

Name: trans-3-Hydroxy Cotinine
Brand: Vaqora Chemicals
SKU: VQ-038614

About trans-3-Hydroxy Cotinine

Vaqora Chemicals supplies trans-3-Hydroxy Cotinine, a metabolite or degradation product of Cotinine registered under CAS number 34834-67-8. With the molecular formula C10H12N2O2, it has a molar mass of 192.21 g/mol. The IUPAC name is (3R,5S)-3-hydroxy-1-methyl-5-pyridin-3-ylpyrrolidin-2-one. It is also known as (3R,5S)-3-Hydroxy Cotinine or Hydroxycotinine.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Under GHS it is labelled “Danger”, so handle it with suitable PPE and consult the SDS.

It is used in metabolite identification, stability-indicating method development and impurity profiling of Cotinine, as well as in QC testing and ANDA/DMF documentation. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

We offer trans-3-Hydroxy Cotinine in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling
Fine chemical synthesis

Industries

Related to Cotinine

View every impurity, metabolite and intermediate we list for Cotinine.

Cotinine impurities

Specifications & identifiers

Chemical identifiers
Product name	trans-3-Hydroxy Cotinine
Catalogue No.	VQ-038614
CAS Number	34834-67-8
IUPAC name	(3R,5S)-3-hydroxy-1-methyl-5-pyridin-3-ylpyrrolidin-2-one
Molecular formula	C₁₀H₁₂N₂O₂
Molecular weight	192.21 g/mol
Exact mass	192.0899
Grade	Reference Standard
HSN code	38229090
InChIKey	XOKCJXZZNAUIQN-DTWKUNHWSA-N
SMILES	CN1[C@@H](C[C@H](C1=O)O)C2=CN=CC=C2
PubChem CID	107963

Physical properties
Physical form	Solid
LogP (XLogP3)	-0.9
H-bond donors / acceptors	1 / 3
TPSA	53.4 Å²
Synonyms	(3R,5S)-3-Hydroxy Cotinine, (3R,5S)-3-hydroxy-1-methyl-5-(pyridin-3-yl)pyrrolidin-2-one, Hydroxycotinine, 3-Hydroxy-1-methyl-5-(3-pyridinyl)-2-pyrrolidinone, Trans-3-hydroxy-1-methyl-5-(pyridin-3-yl)pyrrolidin-2-one, 2-Pyrrolidinone, 3-hydroxy-1-methyl-5-(3-pyridinyl)-, (3R,5S)-, (3R-trans)-3-hydroxy-1-methyl-5-(3-pyridinyl)-2-Pyrrolidinone, 3-hydroxy-1-methyl-5-pyridin-3-yl-pyrrolidin-2-one, (3'R,5'S)-3'-Hydroxycotinine

Safety & hazard information (GHS)

Toxic

Signal word: Danger

Hazard statements

H301Toxic if swallowed

Precautionary statements: P264, P270, P301 + P316, P321, P330, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of trans-3-Hydroxy Cotinine?

The CAS Registry Number of trans-3-Hydroxy Cotinine is 34834-67-8. It is also known as (3R,5S)-3-Hydroxy Cotinine, (3R,5S)-3-hydroxy-1-methyl-5-(pyridin-3-yl)pyrrolidin-2-one, Hydroxycotinine.

What is the molecular formula and molecular weight of trans-3-Hydroxy Cotinine?

trans-3-Hydroxy Cotinine has the molecular formula C10H12N2O2 and a molecular weight of 192.21 g/mol. Its IUPAC name is (3R,5S)-3-hydroxy-1-methyl-5-pyridin-3-ylpyrrolidin-2-one.

What is trans-3-Hydroxy Cotinine used for?

trans-3-Hydroxy Cotinine is supplied as a characterised reference material related to Cotinine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of trans-3-Hydroxy Cotinine can I order?

We supply trans-3-Hydroxy Cotinine in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with trans-3-Hydroxy Cotinine?

Yes. Every lot of trans-3-Hydroxy Cotinine is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can trans-3-Hydroxy Cotinine be shipped internationally?

Yes. trans-3-Hydroxy Cotinine is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.