3-Amino-4-methoxybenzotrifluoride

Name: 3-Amino-4-methoxybenzotrifluoride
Brand: Vaqora Chemicals
SKU: VQ-041058

About 3-Amino-4-methoxybenzotrifluoride

Listed under CAS 349-65-5, 3-Amino-4-methoxybenzotrifluoride is a process intermediate or related compound of Letermovir available from Vaqora Chemicals. The compound has the formula C8H8F3NO, corresponding to a molecular weight of 191.15 g/mol. Its systematic (IUPAC) name is 2-methoxy-5-(trifluoromethyl)aniline. Alternative names: 2-Amino-4-trifluoromethylanisole and Benzenamine, 2-methoxy-5-(trifluoromethyl)-.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

Process chemists and analysts use it when developing synthetic routes to Letermovir, tracking process-related impurities and validating analytical methods. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, 3-Amino-4-methoxybenzotrifluoride is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

API route development
Impurity fate & purge studies
Analytical method development
Fine chemical synthesis

Industries

Related to Letermovir

View every impurity, metabolite and intermediate we list for Letermovir.

Letermovir impurities

Specifications & identifiers

Chemical identifiers
Product name	3-Amino-4-methoxybenzotrifluoride
Catalogue No.	VQ-041058
CAS Number	349-65-5
IUPAC name	2-methoxy-5-(trifluoromethyl)aniline
Molecular formula	C₈H₈F₃NO
Molecular weight	191.15 g/mol
Exact mass	191.0558
HSN code	2933
InChIKey	RKUSRLUGUVDNKP-UHFFFAOYSA-N
SMILES	COC1=C(C=C(C=C1)C(F)(F)F)N
PubChem CID	600637

Physical properties
Physical form	Solid
LogP (XLogP3)	2.3
H-bond donors / acceptors	1 / 5
TPSA	35.3 Å²
Synonyms	2-Amino-4-trifluoromethylanisole, Benzenamine, 2-methoxy-5-(trifluoromethyl)-, 2-methoxy-5-(trifluoromethyl)benzenamine, 2-Methoxy-5-trifluoromethylaniline, 2-Amino-4-(trifluoromethyl)anisole, 5-(Trifluoromethyl)-2-methoxyaniline, 2-Methoxy-5-trifluoromethyl-phenylamine, 6-Methoxy-.alpha.,.alpha.,.alpha.-trifluoro-m-toluidine, 2-Methoxy-5-(trifluoromethyl)phenylamine, 5-(Trifluoromethyl)-o-anisidine, 4-trifluromethyl-o-anisidine, 2-methoxy-5-trifluoromethyl-aniline

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H312Harmful in contact with skin
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P317, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 3-Amino-4-methoxybenzotrifluoride?

The CAS Registry Number of 3-Amino-4-methoxybenzotrifluoride is 349-65-5. It is also known as 2-Amino-4-trifluoromethylanisole, Benzenamine, 2-methoxy-5-(trifluoromethyl)-, 2-methoxy-5-(trifluoromethyl)benzenamine.

What is the molecular formula and molecular weight of 3-Amino-4-methoxybenzotrifluoride?

3-Amino-4-methoxybenzotrifluoride has the molecular formula C8H8F3NO and a molecular weight of 191.15 g/mol. Its IUPAC name is 2-methoxy-5-(trifluoromethyl)aniline.

What is 3-Amino-4-methoxybenzotrifluoride used for?

3-Amino-4-methoxybenzotrifluoride is supplied as a characterised reference material related to Letermovir. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 3-Amino-4-methoxybenzotrifluoride can I order?

We supply 3-Amino-4-methoxybenzotrifluoride, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 3-Amino-4-methoxybenzotrifluoride?

Yes. Every lot of 3-Amino-4-methoxybenzotrifluoride is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 3-Amino-4-methoxybenzotrifluoride be shipped internationally?

Yes. 3-Amino-4-methoxybenzotrifluoride is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.