4,6-Dimethyl-2-Methylsulfonyl-Pyrimidine

Name: 4,6-Dimethyl-2-Methylsulfonyl-Pyrimidine
Brand: Vaqora Chemicals
SKU: VQ-029088

About 4,6-Dimethyl-2-Methylsulfonyl-Pyrimidine

Listed under CAS 35144-22-0, 4,6-Dimethyl-2-Methylsulfonyl-Pyrimidine is an impurity of Ambrisentan available from Vaqora Chemicals. Formula C7H10N2O2S, molecular weight 186.23 g/mol. It is also known as pyrimidine, 4,6-dimethyl-2-(methylsulfonyl)- or 2-Methanesulfonyl-4,6-dimethylpyrimidine.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. It carries the GHS signal word “Danger” with 6 hazard statements. Review the Safety Data Sheet before use.

Pharmaceutical QC and development laboratories use this impurity standard of Ambrisentan to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. It is used across pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Ambrisentan

View every impurity, metabolite and intermediate we list for Ambrisentan.

Ambrisentan impurities

Specifications & identifiers

Chemical identifiers
Product name	4,6-Dimethyl-2-Methylsulfonyl-Pyrimidine
Catalogue No.	VQ-029088
CAS Number	35144-22-0
IUPAC name	4,6-dimethyl-2-methylsulfonylpyrimidine
Molecular formula	C₇H₁₀N₂O₂S
Molecular weight	186.23 g/mol
Exact mass	186.0463
Grade	Reference Standard
HSN code	38229090
InChIKey	ZHPSNGCLCHWTRG-UHFFFAOYSA-N
SMILES	CC1=CC(=NC(=N1)S(=O)(=O)C)C
PubChem CID	2772382

Physical properties
Physical form	Solid
LogP (XLogP3)	0.6
H-bond donors / acceptors	0 / 4
TPSA	68.3 Å²
Synonyms	pyrimidine, 4,6-dimethyl-2-(methylsulfonyl)-, 2-Methanesulfonyl-4,6-dimethylpyrimidine, 2-methane-sulfonyl-4,6-dimethyl-pyrimidine, 4,6-dimethyl-2-(methylsulphonyl)pyrimidine, 4,6-dimethyl-2-methanesulphonyl pyri, 2-methanesulfonyl-4,6-dimethy-pyrimidine, 2-(Methanesulfonyl)-4,6-dimethylpyrimidine, 4,6-dimethyl-2-methanesulphonyl pyrimidine

Safety & hazard information (GHS)

Harmful / irritant

Health hazard

Signal word: Danger

Hazard statements

H315Causes skin irritation
H317May cause an allergic skin reaction
H319Causes serious eye irritation
H334May cause allergy or asthma symptoms or breathing difficulties if inhaled
H335May cause respiratory irritation
H361Suspected of damaging fertility or the unborn child

Precautionary statements: P203, P233, P260, P261, P264, P264 + P265, P271, P272, P280, P284, P302 + P352, P304 + P340, P305 + P351 + P338, P318, P319, P321, P332 + P317, P333 + P317, P337 + P317, P342 + P316, P362 + P364, P403, P403 + P233, P405

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 4,6-Dimethyl-2-Methylsulfonyl-Pyrimidine?

The CAS Registry Number of 4,6-Dimethyl-2-Methylsulfonyl-Pyrimidine is 35144-22-0. It is also known as pyrimidine, 4,6-dimethyl-2-(methylsulfonyl)-, 2-Methanesulfonyl-4,6-dimethylpyrimidine, 2-methane-sulfonyl-4,6-dimethyl-pyrimidine.

What is the molecular formula and molecular weight of 4,6-Dimethyl-2-Methylsulfonyl-Pyrimidine?

4,6-Dimethyl-2-Methylsulfonyl-Pyrimidine has the molecular formula C7H10N2O2S and a molecular weight of 186.23 g/mol. Its IUPAC name is 4,6-dimethyl-2-methylsulfonylpyrimidine.

What is 4,6-Dimethyl-2-Methylsulfonyl-Pyrimidine used for?

4,6-Dimethyl-2-Methylsulfonyl-Pyrimidine is supplied as a characterised reference material related to Ambrisentan. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 4,6-Dimethyl-2-Methylsulfonyl-Pyrimidine can I order?

We supply 4,6-Dimethyl-2-Methylsulfonyl-Pyrimidine in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 4,6-Dimethyl-2-Methylsulfonyl-Pyrimidine?

Yes. Every lot of 4,6-Dimethyl-2-Methylsulfonyl-Pyrimidine is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 4,6-Dimethyl-2-Methylsulfonyl-Pyrimidine be shipped internationally?

Yes. 4,6-Dimethyl-2-Methylsulfonyl-Pyrimidine is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.