Methylefavirenz

Name: Methylefavirenz
Brand: Vaqora Chemicals
SKU: VQ-022493

About Methylefavirenz

Methylefavirenz is an impurity of Efavirenz carrying the CAS registry number 353270-76-5. Formula C15H11ClF3NO2, molecular weight 329.7 g/mol. Its systematic (IUPAC) name is (4S)-6-chloro-4-[2-(2-methylcyclopropyl)ethynyl]-4-(trifluoromethyl)-1H-3,1-benzoxazin-2-one. It is also known as Racemic Methyl Efavirenz or SV 99.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Good laboratory practice and suitable PPE are recommended during handling.

As a characterised impurity of Efavirenz, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. It is used across pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Methylefavirenz in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Efavirenz

View every impurity, metabolite and intermediate we list for Efavirenz.

Efavirenz impurities

Specifications & identifiers

Chemical identifiers
Product name	Methylefavirenz
Catalogue No.	VQ-022493
CAS Number	353270-76-5
IUPAC name	(4S)-6-chloro-4-[2-(2-methylcyclopropyl)ethynyl]-4-(trifluoromethyl)-1H-3,1-benzoxazin-2-one
Molecular formula	C₁₅H₁₁ClF₃NO₂
Molecular weight	329.7 g/mol
Exact mass	329.043
Grade	Reference Standard
HSN code	38229090
InChIKey	VTRDGEWILKMMRP-CTCYHXBNSA-N
SMILES	CC1CC1C#C[C@]2(C3=C(C=CC(=C3)Cl)NC(=O)O2)C(F)(F)F
PubChem CID	71587715

Physical properties
Physical form	Solid
LogP (XLogP3)	4.3
H-bond donors / acceptors	1 / 5
TPSA	38.3 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Methylefavirenz?

The CAS Registry Number of Methylefavirenz is 353270-76-5. It is also known as Racemic Methyl Efavirenz, SV 99, SV-997.

What is the molecular formula and molecular weight of Methylefavirenz?

Methylefavirenz has the molecular formula C15H11ClF3NO2 and a molecular weight of 329.7 g/mol. Its IUPAC name is (4S)-6-chloro-4-[2-(2-methylcyclopropyl)ethynyl]-4-(trifluoromethyl)-1H-3,1-benzoxazin-2-one.

What is Methylefavirenz used for?

Methylefavirenz is supplied as a characterised reference material related to Efavirenz. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Methylefavirenz can I order?

We supply Methylefavirenz in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Methylefavirenz?

Yes. Every lot of Methylefavirenz is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Methylefavirenz be shipped internationally?

Yes. We export Methylefavirenz worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.