Methyl (S)-3-amino-3-(4-chlorophenyl)-2,2-dim… 357388-75-1

About Methyl (S)-3-amino-3-(4-chlorophenyl)-2,2-dimethylpropanoate

Methyl (S)-3-amino-3-(4-chlorophenyl)-2,2-dimethylpropanoate is an impurity of Capivasertib carrying the CAS registry number 357388-75-1. With the molecular formula C12H16ClNO2, it has a molar mass of 241.71 g/mol. The IUPAC name is methyl (3S)-3-amino-3-(4-chlorophenyl)-2,2-dimethylpropanoate.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Handle it with standard laboratory precautions and appropriate personal protective equipment.

Pharmaceutical QC and development laboratories use this impurity standard of Capivasertib to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

We offer Methyl (S)-3-amino-3-(4-chlorophenyl)-2,2-dimethylpropanoate in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Capivasertib

View every impurity, metabolite and intermediate we list for Capivasertib.

Capivasertib impurities

Specifications & identifiers

Chemical identifiers
Product name	Methyl (S)-3-amino-3-(4-chlorophenyl)-2,2-dimethylpropanoate
Catalogue No.	VQ-029626
CAS Number	357388-75-1
IUPAC name	methyl (3S)-3-amino-3-(4-chlorophenyl)-2,2-dimethylpropanoate
Molecular formula	C₁₂H₁₆ClNO₂
Molecular weight	241.71 g/mol
Exact mass	241.087
Grade	Reference Standard
HSN code	38229090
InChIKey	JUMFVXWMGBVSSP-JTQLQIEISA-N
SMILES	CC(C)([C@H](C1=CC=C(C=C1)Cl)N)C(=O)OC
PubChem CID	101139059

Physical properties
Physical form	Solid
LogP (XLogP3)	2.2
H-bond donors / acceptors	1 / 3
TPSA	52.3 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Methyl (S)-3-amino-3-(4-chlorophenyl)-2,2-dimethylpropanoate?

The CAS Registry Number of Methyl (S)-3-amino-3-(4-chlorophenyl)-2,2-dimethylpropanoate is 357388-75-1. It is also known as Methyl-(3s)-3-amino-3-(4-chlorophenyl)-2,2-dimethylpropanoate.

What is the molecular formula and molecular weight of Methyl (S)-3-amino-3-(4-chlorophenyl)-2,2-dimethylpropanoate?

Methyl (S)-3-amino-3-(4-chlorophenyl)-2,2-dimethylpropanoate has the molecular formula C12H16ClNO2 and a molecular weight of 241.71 g/mol. Its IUPAC name is methyl (3S)-3-amino-3-(4-chlorophenyl)-2,2-dimethylpropanoate.

What is Methyl (S)-3-amino-3-(4-chlorophenyl)-2,2-dimethylpropanoate used for?

Methyl (S)-3-amino-3-(4-chlorophenyl)-2,2-dimethylpropanoate is supplied as a characterised reference material related to Capivasertib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Methyl (S)-3-amino-3-(4-chlorophenyl)-2,2-dimethylpropanoate can I order?

We supply Methyl (S)-3-amino-3-(4-chlorophenyl)-2,2-dimethylpropanoate in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Methyl (S)-3-amino-3-(4-chlorophenyl)-2,2-dimethylpropanoate?

Yes. Every lot of Methyl (S)-3-amino-3-(4-chlorophenyl)-2,2-dimethylpropanoate is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Methyl (S)-3-amino-3-(4-chlorophenyl)-2,2-dimethylpropanoate be shipped internationally?

Yes. We export Methyl (S)-3-amino-3-(4-chlorophenyl)-2,2-dimethylpropanoate worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.