Varenicline Impurity 3 (Freebase)

Name: Varenicline Impurity 3 (Freebase)
Brand: Vaqora Chemicals
SKU: VQ-006112

About Varenicline Impurity 3 (Freebase)

Varenicline Impurity 3 (Freebase) (CAS 357424-12-5) is an impurity of Varenicline offered by Vaqora Chemicals, specified at 93% purity. With the molecular formula C12H13N3, it has a molar mass of 199.25 g/mol. Systematically, it is named (1S,11R)-5,7,13-triazatetracyclo[9.3.1.02,10.04,8]pentadeca-2,4(8),5,9-tetraene. Common synonyms include Varenicline Impurity 3.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

As a characterised impurity of Varenicline, it is used for analytical method development, method validation (AMV) and routine quality-control testing, and it supports ANDA and DMF regulatory filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide. This item is currently in stock for prompt dispatch.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Varenicline

View every impurity, metabolite and intermediate we list for Varenicline.

Varenicline impurities

Specifications & identifiers

Chemical identifiers
Product name	Varenicline Impurity 3 (Freebase)
Catalogue No.	VQ-006112
CAS Number	357424-12-5
Other CAS	230615-10-8
IUPAC name	(1S,11R)-5,7,13-triazatetracyclo[9.3.1.02,10.04,8]pentadeca-2,4(8),5,9-tetraene
Molecular formula	C₁₂H₁₃N₃
Molecular weight	199.25 g/mol
Exact mass	199.1109
Grade	Reference Standard
Purity / assay	93%
HSN code	38229090
InChIKey	SPAMUHJHVULSFR-OCAPTIKFSA-N
SMILES	C1[C@H]2CNC[C@@H]1C3=CC4=C(C=C23)NC=N4
PubChem CID	119079025

Physical properties
Physical form	Solid
LogP (XLogP3)	1.1
H-bond donors / acceptors	2 / 2
TPSA	40.7 Å²
Synonyms	1,5,6,7,8,9-Hexahydro-5,9-methanoimidazo[4',5':4,5]benzo[1,2-d]azepine, Varenicline Impurity 3, 1,5,6,7,8,9-Hexahydro-5,9-methanoimidazo[4,5-h][3]benzazepine, 5,9-Methanoimidazo(4,5-H)(3)benzazepine, 1,5,6,7,8,9-hexahydro-, 1,5,6,7,8,9-Hexahydro-5,9-methanoimidazo(4',5':4,5)benzo(1,2-d)azepine, (5S,9R)-1,5,6,7,8,9-hexahydro-5,9-methanoimidazo[4',5':4,5]benzo[1,2-d]azepine

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Varenicline Impurity 3 (Freebase)?

The CAS Registry Number of Varenicline Impurity 3 (Freebase) is 357424-12-5. It is also known as 1,5,6,7,8,9-Hexahydro-5,9-methanoimidazo[4',5':4,5]benzo[1,2-d]azepine, Varenicline Impurity 3, 1,5,6,7,8,9-Hexahydro-5,9-methanoimidazo[4,5-h][3]benzazepine.

What is the molecular formula and molecular weight of Varenicline Impurity 3 (Freebase)?

Varenicline Impurity 3 (Freebase) has the molecular formula C12H13N3 and a molecular weight of 199.25 g/mol. Its IUPAC name is (1S,11R)-5,7,13-triazatetracyclo[9.3.1.02,10.04,8]pentadeca-2,4(8),5,9-tetraene.

What is Varenicline Impurity 3 (Freebase) used for?

Varenicline Impurity 3 (Freebase) is supplied as a characterised reference material related to Varenicline. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Varenicline Impurity 3 (Freebase) can I order?

We supply Varenicline Impurity 3 (Freebase) in Reference Standard (93%) grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Varenicline Impurity 3 (Freebase)?

Yes. Every lot of Varenicline Impurity 3 (Freebase) is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Varenicline Impurity 3 (Freebase) be shipped internationally?

Yes. We export Varenicline Impurity 3 (Freebase) worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.