Boc-3-hydroxy-1-adamantyl-D-glycine

Name: Boc-3-hydroxy-1-adamantyl-D-glycine
Brand: Vaqora Chemicals
SKU: VQ-027088

About Boc-3-hydroxy-1-adamantyl-D-glycine

Boc-3-hydroxy-1-adamantyl-D-glycine is a metabolite or degradation product of Saxagliptin carrying the CAS registry number 361442-00-4. Formula C17H27NO5, molecular weight 325.4 g/mol. Systematically, it is named (2S)-2-(3-hydroxy-1-adamantyl)-2-[(2-methylpropan-2-yl)oxycarbonylamino]acetic acid. Common synonyms include (R)-N-Boc-3-hydroxyadamantylglycine and (S)-N-Boc-3-hydroxyadamantylglycine.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

Analytical teams use this compound to identify metabolites and degradants of Saxagliptin, to validate stability-indicating methods (AMV) and to support QC and regulatory filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Boc-3-hydroxy-1-adamantyl-D-glycine in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Saxagliptin

View every impurity, metabolite and intermediate we list for Saxagliptin.

Saxagliptin impurities

Specifications & identifiers

Chemical identifiers
Product name	Boc-3-hydroxy-1-adamantyl-D-glycine
Catalogue No.	VQ-027088
CAS Number	361442-00-4
IUPAC name	(2S)-2-(3-hydroxy-1-adamantyl)-2-[(2-methylpropan-2-yl)oxycarbonylamino]acetic acid
Molecular formula	C₁₇H₂₇NO₅
Molecular weight	325.4 g/mol
Exact mass	325.1889
Grade	Reference Standard
HSN code	38229090
InChIKey	UKCKDSNFBFHSHC-ZEJPWUNMSA-N
SMILES	CC(C)(C)OC(=O)N[C@H](C(=O)O)C12CC3CC(C1)CC(C3)(C2)O
PubChem CID	11723843

Physical properties
Physical form	Solid
LogP (XLogP3)	2
H-bond donors / acceptors	3 / 5
TPSA	95.9 Å²
Synonyms	(2S)-2-((tert-Butoxycarbonyl)amino)-2-(3-hydroxyadamantan-1-yl)acetic acid, (2S)-[(tert-Butoxycarbonyl)amino](3-hydroxytricyclo[3.3.1.13,7]decan-1-yl)ethanoic acid, (R)-N-Boc-3-hydroxyadamantylglycine, (S)-2-(Boc-amino)-2-(3-hydroxy-1-adamantanyl)acetic Acid, (2S)-2-{[(tert-butoxy)carbonyl]amino}-2-(3-hydroxyadamantan-1-yl)acetic acid, (S)-N-Boc-3-hydroxyadamantylglycine, (2S)-[(tert-Butoxycarbonyl)amino]-2-(3-hydroxytricyclo[3.3.1.1(3,7)]dec-1-yl)acetic Acid, (S)-2-((tert-Butoxycarbonyl)amino)-2-((1r,3R,5R,7S)-3-hydroxyadamantan-1-yl)acetic acid, (2S)-2-((tert-Butoxycarbonyl)amino)-2-(3-hydroxyadamantan-1-yl)aceticacid, (2S)-2-(tert-butoxycarbonylamino)-2-(3-hydroxy-1-adamantyl)acetic acid

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Boc-3-hydroxy-1-adamantyl-D-glycine?

The CAS Registry Number of Boc-3-hydroxy-1-adamantyl-D-glycine is 361442-00-4. It is also known as (2S)-2-((tert-Butoxycarbonyl)amino)-2-(3-hydroxyadamantan-1-yl)acetic acid, (2S)-[(tert-Butoxycarbonyl)amino](3-hydroxytricyclo[3.3.1.13,7]decan-1-yl)ethanoic acid, (R)-N-Boc-3-hydroxyadamantylglycine.

What is the molecular formula and molecular weight of Boc-3-hydroxy-1-adamantyl-D-glycine?

Boc-3-hydroxy-1-adamantyl-D-glycine has the molecular formula C17H27NO5 and a molecular weight of 325.4 g/mol. Its IUPAC name is (2S)-2-(3-hydroxy-1-adamantyl)-2-[(2-methylpropan-2-yl)oxycarbonylamino]acetic acid.

What is Boc-3-hydroxy-1-adamantyl-D-glycine used for?

Boc-3-hydroxy-1-adamantyl-D-glycine is supplied as a characterised reference material related to Saxagliptin. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Boc-3-hydroxy-1-adamantyl-D-glycine can I order?

We supply Boc-3-hydroxy-1-adamantyl-D-glycine in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Boc-3-hydroxy-1-adamantyl-D-glycine?

Yes. Every lot of Boc-3-hydroxy-1-adamantyl-D-glycine is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Boc-3-hydroxy-1-adamantyl-D-glycine be shipped internationally?

Yes. We export Boc-3-hydroxy-1-adamantyl-D-glycine worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.