Tramadol Hydrochloride

Name: Tramadol Hydrochloride
Brand: Vaqora Chemicals
SKU: VQ-007812

About Tramadol Hydrochloride

Tramadol Hydrochloride (CAS 36282-47-0) is a high-purity reference standard of Tramadol offered by Vaqora Chemicals. Formula C16H26ClNO2, molecular weight 299.83 g/mol. Its systematic (IUPAC) name is cis-(1R,2R)-2-[(dimethylamino)methyl]-1-(3-methoxyphenyl)cyclohexan-1-ol. Hydrochloride. Common synonyms include cis-Tramadol hydrochloride and Tramadex.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Under GHS it is labelled “Danger”, so handle it with suitable PPE and consult the SDS.

Laboratories use this Tramadol standard for identity and assay testing, system suitability checks and method validation supporting ANDA and DMF filings. It is used across pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide. This item is currently in stock for prompt dispatch.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Tramadol

View every impurity, metabolite and intermediate we list for Tramadol.

Tramadol impurities

Specifications & identifiers

Chemical identifiers
Product name	Tramadol Hydrochloride
Catalogue No.	VQ-007812
CAS Number	36282-47-0
Other CAS	27203-92-5
IUPAC name	cis-(1R,2R)-2-[(dimethylamino)methyl]-1-(3-methoxyphenyl)cyclohexan-1-ol;hydrochloride
Molecular formula	C₁₆H₂₆ClNO₂
Molecular weight	299.83 g/mol
Exact mass	299.1652
Grade	Reference Standard
HSN code	38229090
InChIKey	PPKXEPBICJTCRU-XMZRARIVSA-N
SMILES	CN(C)C[C@H]1CCCC[C@@]1(C2=CC(=CC=C2)OC)O.Cl
PubChem CID	63013

Physical properties
Physical form	Solid
H-bond donors / acceptors	2 / 3
TPSA	32.7 Å²
Synonyms	(1R,2R)-2-((dimethylamino)methyl)-1-(3-methoxyphenyl)cyclohexanol Hydrochloride, cis-Tramadol hydrochloride, (±)-trans-2-[(Dimethylamino)methyl]-1-(m-methoxyphenyl)cyclohexanol hydrochloride, Tramadex, Dolana Dolotram Ira-Tramadol Mabron, Melanate, Omnidol, Poltram, Radol, Tadol, Tedamol, Topalgic

Safety & hazard information (GHS)

Toxic

Harmful / irritant

Environmental hazard

Signal word: Danger

Hazard statements

H301Toxic if swallowed
H302Harmful if swallowed
H411Toxic to aquatic life with long lasting effects

Precautionary statements: P264, P270, P273, P301 + P316, P301 + P317, P321, P330, P391, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Tramadol Hydrochloride?

The CAS Registry Number of Tramadol Hydrochloride is 36282-47-0. It is also known as (1R,2R)-2-((dimethylamino)methyl)-1-(3-methoxyphenyl)cyclohexanol Hydrochloride, cis-Tramadol hydrochloride, (±)-trans-2-[(Dimethylamino)methyl]-1-(m-methoxyphenyl)cyclohexanol hydrochloride.

What is the molecular formula and molecular weight of Tramadol Hydrochloride?

Tramadol Hydrochloride has the molecular formula C16H26ClNO2 and a molecular weight of 299.83 g/mol.

What is Tramadol Hydrochloride used for?

Tramadol Hydrochloride is supplied as a characterised reference material related to Tramadol. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Tramadol Hydrochloride can I order?

We supply Tramadol Hydrochloride in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg, 500 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Tramadol Hydrochloride?

Yes. Every lot of Tramadol Hydrochloride is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Tramadol Hydrochloride be shipped internationally?

Yes. Tramadol Hydrochloride is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.