Cyclo-Gly-Pro

Name: Cyclo-Gly-Pro
Brand: Vaqora Chemicals
SKU: VQ-039089

About Cyclo-Gly-Pro

Listed under CAS 3705-27-9, Cyclo-Gly-Pro is an impurity of Vildagliptin available from Vaqora Chemicals. Its molecular formula is C7H10N2O2 and its molecular weight is 154.17 g/mol. The IUPAC name is (8aS)-2,3,6,7,8,8a-hexahydropyrrolo[1,2-a]pyrazine-1,4-dione. Alternative names: Cyclo(prolylglycyl) and Traneurocin.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

Pharmaceutical QC and development laboratories use this impurity standard of Vildagliptin to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. It is used across pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, Cyclo-Gly-Pro is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Vildagliptin

View every impurity, metabolite and intermediate we list for Vildagliptin.

Vildagliptin impurities

Specifications & identifiers

Chemical identifiers
Product name	Cyclo-Gly-Pro
Catalogue No.	VQ-039089
CAS Number	3705-27-9
IUPAC name	(8aS)-2,3,6,7,8,8a-hexahydropyrrolo[1,2-a]pyrazine-1,4-dione
Molecular formula	C₇H₁₀N₂O₂
Molecular weight	154.17 g/mol
Exact mass	154.0742
Grade	Reference Standard
HSN code	38229090
InChIKey	OWOHLURDBZHNGG-YFKPBYRVSA-N
SMILES	C1C[C@H]2C(=O)NCC(=O)N2C1
PubChem CID	126154

Physical properties
Physical form	Solid
LogP (XLogP3)	-0.6
H-bond donors / acceptors	1 / 2
TPSA	49.4 Å²
Synonyms	Cyclo(prolylglycyl), Traneurocin, Cyclo-prolylglycine, Cyclo(pro-gly), Cyclo(pro-O-gly), Na 831, NA-831, (S)-Hexahydropyrrolo(1,2-a)pyrazine-1,4-dione-4-17O, Pyrrolo(1,2-a)pyrazine-1,4-dione-4-170, hexahydro-, (S)-, cycloprolylglycine, cyclo(prolyl-glycyl), cyclo-(Pro-Gly)

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P271, P280, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Cyclo-Gly-Pro?

The CAS Registry Number of Cyclo-Gly-Pro is 3705-27-9. It is also known as Cyclo(prolylglycyl), Traneurocin, Cyclo-prolylglycine.

What is the molecular formula and molecular weight of Cyclo-Gly-Pro?

Cyclo-Gly-Pro has the molecular formula C7H10N2O2 and a molecular weight of 154.17 g/mol. Its IUPAC name is (8aS)-2,3,6,7,8,8a-hexahydropyrrolo[1,2-a]pyrazine-1,4-dione.

What is Cyclo-Gly-Pro used for?

Cyclo-Gly-Pro is supplied as a characterised reference material related to Vildagliptin. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Cyclo-Gly-Pro can I order?

We supply Cyclo-Gly-Pro in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Cyclo-Gly-Pro?

Yes. Every lot of Cyclo-Gly-Pro is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Cyclo-Gly-Pro be shipped internationally?

Yes. Cyclo-Gly-Pro is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.