Methyl 4-(4-fluorophenyl)-6-isopropyl-2-(meth… 371775-70-1

About Methyl 4-(4-fluorophenyl)-6-isopropyl-2-(methylsulfonamido)pyrimidine-5-carboxylate

Methyl 4-(4-fluorophenyl)-6-isopropyl-2-(methylsulfonamido)pyrimidine-5-carboxylate is an impurity of Rosuvastatin carrying the CAS registry number 371775-70-1. With the molecular formula C16H18FN3O4S, it has a molar mass of 367.4 g/mol. Systematically, it is named methyl 4-(4-fluorophenyl)-2-(methanesulfonamido)-6-propan-2-ylpyrimidine-5-carboxylate.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Good laboratory practice and suitable PPE are recommended during handling.

Pharmaceutical QC and development laboratories use this impurity standard of Rosuvastatin to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

We offer Methyl 4-(4-fluorophenyl)-6-isopropyl-2-(methylsulfonamido)pyrimidine-5-carboxylate in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Rosuvastatin

View every impurity, metabolite and intermediate we list for Rosuvastatin.

Rosuvastatin impurities

Specifications & identifiers

Chemical identifiers
Product name	Methyl 4-(4-fluorophenyl)-6-isopropyl-2-(methylsulfonamido)pyrimidine-5-carboxylate
Catalogue No.	VQ-044675
CAS Number	371775-70-1
IUPAC name	methyl 4-(4-fluorophenyl)-2-(methanesulfonamido)-6-propan-2-ylpyrimidine-5-carboxylate
Molecular formula	C₁₆H₁₈FN₃O₄S
Molecular weight	367.4 g/mol
Exact mass	367.1002
Grade	Reference Standard
HSN code	38229090
InChIKey	JVDSNUDYCSSSBP-UHFFFAOYSA-N
SMILES	CC(C)C1=NC(=NC(=C1C(=O)OC)C2=CC=C(C=C2)F)NS(=O)(=O)C
PubChem CID	53433094

Physical properties
Physical form	Solid
LogP (XLogP3)	2.3
H-bond donors / acceptors	1 / 8
TPSA	107 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Methyl 4-(4-fluorophenyl)-6-isopropyl-2-(methylsulfonamido)pyrimidine-5-carboxylate?

The CAS Registry Number of Methyl 4-(4-fluorophenyl)-6-isopropyl-2-(methylsulfonamido)pyrimidine-5-carboxylate is 371775-70-1. It is also known as 5-Methyl Formate De(3,5-dihydroxyhept-6-enoate) Rosuvastatin.

What is the molecular formula and molecular weight of Methyl 4-(4-fluorophenyl)-6-isopropyl-2-(methylsulfonamido)pyrimidine-5-carboxylate?

Methyl 4-(4-fluorophenyl)-6-isopropyl-2-(methylsulfonamido)pyrimidine-5-carboxylate has the molecular formula C16H18FN3O4S and a molecular weight of 367.4 g/mol. Its IUPAC name is methyl 4-(4-fluorophenyl)-2-(methanesulfonamido)-6-propan-2-ylpyrimidine-5-carboxylate.

What is Methyl 4-(4-fluorophenyl)-6-isopropyl-2-(methylsulfonamido)pyrimidine-5-carboxylate used for?

Methyl 4-(4-fluorophenyl)-6-isopropyl-2-(methylsulfonamido)pyrimidine-5-carboxylate is supplied as a characterised reference material related to Rosuvastatin. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Methyl 4-(4-fluorophenyl)-6-isopropyl-2-(methylsulfonamido)pyrimidine-5-carboxylate can I order?

We supply Methyl 4-(4-fluorophenyl)-6-isopropyl-2-(methylsulfonamido)pyrimidine-5-carboxylate in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Methyl 4-(4-fluorophenyl)-6-isopropyl-2-(methylsulfonamido)pyrimidine-5-carboxylate?

Yes. Every lot of Methyl 4-(4-fluorophenyl)-6-isopropyl-2-(methylsulfonamido)pyrimidine-5-carboxylate is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Methyl 4-(4-fluorophenyl)-6-isopropyl-2-(methylsulfonamido)pyrimidine-5-carboxylate be shipped internationally?

Yes. We export Methyl 4-(4-fluorophenyl)-6-isopropyl-2-(methylsulfonamido)pyrimidine-5-carboxylate worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.