3-Carbethoxy-2-piperidone

Name: 3-Carbethoxy-2-piperidone
Brand: Vaqora Chemicals
SKU: VQ-044368

About 3-Carbethoxy-2-piperidone

3-Carbethoxy-2-piperidone is an impurity of Melatonin carrying the CAS registry number 3731-16-6. Formula C8H13NO3, molecular weight 171.19 g/mol. The IUPAC name is ethyl 2-oxopiperidine-3-carboxylate. Common synonyms include Ethyl 2-oxo-3-piperidinecarboxylate and 3-Ethoxycarbonyl-2-piperidone.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. It carries the GHS signal word “Warning” with 3 hazard statements. Review the Safety Data Sheet before use.

This Melatonin impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. It is used across pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies 3-Carbethoxy-2-piperidone in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Melatonin

View every impurity, metabolite and intermediate we list for Melatonin.

Melatonin impurities

Specifications & identifiers

Chemical identifiers
Product name	3-Carbethoxy-2-piperidone
Catalogue No.	VQ-044368
CAS Number	3731-16-6
IUPAC name	ethyl 2-oxopiperidine-3-carboxylate
Molecular formula	C₈H₁₃NO₃
Molecular weight	171.19 g/mol
Exact mass	171.0895
Grade	Reference Standard
HSN code	38229090
InChIKey	DUMNOWYWTAYLJN-UHFFFAOYSA-N
SMILES	CCOC(=O)C1CCCNC1=O
PubChem CID	97773

Physical properties
Physical form	Solid
LogP (XLogP3)	0.5
H-bond donors / acceptors	1 / 3
TPSA	55.4 Å²
Synonyms	Ethyl 2-oxo-3-piperidinecarboxylate, 3-Ethoxycarbonyl-2-piperidone, 3-Piperidinecarboxylic acid, 2-oxo-, ethyl ester, Ethyl 2-piperidone-3-carboxylate, 3-Carbethoxy piperidone-2, Ethyl 2-oxo-3-piperidinecarboxylate #, 2-Oxo-piperidine-3-carboxylic acid ethyl ester, 3-Carboxylicacid-2-piperidinone ethyl ester, 2-Oxo-3-piperidinecarboxylic Acid Ethyl Ester, Ethyl 2-oxonipecotate, 3-carboethoxy-2-piperidone, 3-carbethoxy-2-piperidinone

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P271, P280, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 3-Carbethoxy-2-piperidone?

The CAS Registry Number of 3-Carbethoxy-2-piperidone is 3731-16-6. It is also known as Ethyl 2-oxo-3-piperidinecarboxylate, 3-Ethoxycarbonyl-2-piperidone, 3-Piperidinecarboxylic acid, 2-oxo-, ethyl ester.

What is the molecular formula and molecular weight of 3-Carbethoxy-2-piperidone?

3-Carbethoxy-2-piperidone has the molecular formula C8H13NO3 and a molecular weight of 171.19 g/mol. Its IUPAC name is ethyl 2-oxopiperidine-3-carboxylate.

What is 3-Carbethoxy-2-piperidone used for?

3-Carbethoxy-2-piperidone is supplied as a characterised reference material related to Melatonin. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 3-Carbethoxy-2-piperidone can I order?

We supply 3-Carbethoxy-2-piperidone in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 3-Carbethoxy-2-piperidone?

Yes. Every lot of 3-Carbethoxy-2-piperidone is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 3-Carbethoxy-2-piperidone be shipped internationally?

Yes. 3-Carbethoxy-2-piperidone is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.