2'-Hydroxy-3'-nitro-[1,1'-biphenyl]-3-carboxy… 376591-95-6

Name: 2'-Hydroxy-3'-nitro-[1,1'-biphenyl]-3-carboxylic Acid
Brand: Vaqora Chemicals
SKU: VQ-032625

About 2'-Hydroxy-3'-nitro-[1,1'-biphenyl]-3-carboxylic Acid

Vaqora Chemicals supplies 2'-Hydroxy-3'-nitro-[1,1'-biphenyl]-3-carboxylic Acid, a metabolite or degradation product of Eltrombopag registered under CAS number 376591-95-6. Its molecular formula is C13H9NO5 and its molecular weight is 259.21 g/mol. Its systematic (IUPAC) name is 3-(2-hydroxy-3-nitrophenyl)benzoic acid. It is also known as 3-(2-hydroxy-3-nitro-phenyl)benzoic acid or 3'-Nitro-2'-hydroxybiphenyl-3-carboxylic acid.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Good laboratory practice and suitable PPE are recommended during handling.

It is used in metabolite identification, stability-indicating method development and impurity profiling of Eltrombopag, as well as in QC testing and ANDA/DMF documentation. Our customers for this product work in pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling
Fine chemical synthesis

Industries

Related to Eltrombopag

View every impurity, metabolite and intermediate we list for Eltrombopag.

Eltrombopag impurities

Specifications & identifiers

Chemical identifiers
Product name	2'-Hydroxy-3'-nitro-[1,1'-biphenyl]-3-carboxylic Acid
Catalogue No.	VQ-032625
CAS Number	376591-95-6
IUPAC name	3-(2-hydroxy-3-nitrophenyl)benzoic acid
Molecular formula	C₁₃H₉NO₅
Molecular weight	259.21 g/mol
Exact mass	259.0481
Grade	Reference Standard
HSN code	38229090
InChIKey	JCFPSTQCDAZKJN-UHFFFAOYSA-N
SMILES	C1=CC(=CC(=C1)C(=O)O)C2=C(C(=CC=C2)[N+](=O)[O-])O
PubChem CID	22505712

Physical properties
Physical form	Solid
LogP (XLogP3)	3.1
H-bond donors / acceptors	2 / 5
TPSA	103 Å²
Synonyms	[1,1'-Biphenyl]-3-carboxylicacid, 2'-hydroxy-3'-nitro-, 3-(2-hydroxy-3-nitro-phenyl)benzoic acid, [1,1'-Biphenyl]-3-carboxylic acid, 2'-hydroxy-3'-nitro-, 3'-Nitro-2'-hydroxybiphenyl-3-carboxylic acid, 3trade mark-Nitro-2trade mark-hydroxy[1,1trade mark]-biphenyl-3-carboxylic Acid

Safety & hazard information (GHS)

Harmful / irritant

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 2'-Hydroxy-3'-nitro-[1,1'-biphenyl]-3-carboxylic Acid?

The CAS Registry Number of 2'-Hydroxy-3'-nitro-[1,1'-biphenyl]-3-carboxylic Acid is 376591-95-6. It is also known as [1,1'-Biphenyl]-3-carboxylicacid, 2'-hydroxy-3'-nitro-, 3-(2-hydroxy-3-nitro-phenyl)benzoic acid, [1,1'-Biphenyl]-3-carboxylic acid, 2'-hydroxy-3'-nitro-.

What is the molecular formula and molecular weight of 2'-Hydroxy-3'-nitro-[1,1'-biphenyl]-3-carboxylic Acid?

2'-Hydroxy-3'-nitro-[1,1'-biphenyl]-3-carboxylic Acid has the molecular formula C13H9NO5 and a molecular weight of 259.21 g/mol. Its IUPAC name is 3-(2-hydroxy-3-nitrophenyl)benzoic acid.

What is 2'-Hydroxy-3'-nitro-[1,1'-biphenyl]-3-carboxylic Acid used for?

2'-Hydroxy-3'-nitro-[1,1'-biphenyl]-3-carboxylic Acid is supplied as a characterised reference material related to Eltrombopag. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 2'-Hydroxy-3'-nitro-[1,1'-biphenyl]-3-carboxylic Acid can I order?

We supply 2'-Hydroxy-3'-nitro-[1,1'-biphenyl]-3-carboxylic Acid in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 2'-Hydroxy-3'-nitro-[1,1'-biphenyl]-3-carboxylic Acid?

Yes. Every lot of 2'-Hydroxy-3'-nitro-[1,1'-biphenyl]-3-carboxylic Acid is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 2'-Hydroxy-3'-nitro-[1,1'-biphenyl]-3-carboxylic Acid be shipped internationally?

Yes. 2'-Hydroxy-3'-nitro-[1,1'-biphenyl]-3-carboxylic Acid is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.