Eltrombopag Chloro Impurity

About Eltrombopag Chloro Impurity

Eltrombopag Chloro Impurity is a metabolite or degradation product of Eltrombopag carrying the CAS registry number 376592-56-2. With the molecular formula C25H21ClN4O4, it has a molar mass of 476.9 g/mol. The IUPAC name is 3-[5-chloro-3-[[2-(3,4-dimethylphenyl)-5-methyl-3-oxo-1H-pyrazol-4-yl]diazenyl]-2-hydroxyphenyl]benzoic acid. Common synonyms include 5'-Chloro eltrombopag and Eltrombopag Impurity E.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Good laboratory practice and suitable PPE are recommended during handling.

Analytical teams use this compound to identify metabolites and degradants of Eltrombopag, to validate stability-indicating methods (AMV) and to support QC and regulatory filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Eltrombopag

View every impurity, metabolite and intermediate we list for Eltrombopag.

Eltrombopag impurities

Specifications & identifiers

Chemical identifiers
Product name	Eltrombopag Chloro Impurity
Catalogue No.	VQ-025510
CAS Number	376592-56-2
IUPAC name	3-[5-chloro-3-[[2-(3,4-dimethylphenyl)-5-methyl-3-oxo-1H-pyrazol-4-yl]diazenyl]-2-hydroxyphenyl]benzoic acid
Molecular formula	C₂₅H₂₁ClN₄O₄
Molecular weight	476.9 g/mol
Exact mass	476.1251
Grade	Reference Standard
HSN code	38229090
InChIKey	DWTUCKFVPAGHQW-UHFFFAOYSA-N
SMILES	CC1=C(C=C(C=C1)N2C(=O)C(=C(N2)C)N=NC3=CC(=CC(=C3O)C4=CC(=CC=C4)C(=O)O)Cl)C
PubChem CID	136412118

Physical properties
Physical form	Solid
LogP (XLogP3)	6
H-bond donors / acceptors	3 / 7
TPSA	115 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Eltrombopag Chloro Impurity?

The CAS Registry Number of Eltrombopag Chloro Impurity is 376592-56-2. It is also known as 5'-Chloro eltrombopag, Eltrombopag Impurity E.

What is the molecular formula and molecular weight of Eltrombopag Chloro Impurity?

Eltrombopag Chloro Impurity has the molecular formula C25H21ClN4O4 and a molecular weight of 476.9 g/mol. Its IUPAC name is 3-[5-chloro-3-[[2-(3,4-dimethylphenyl)-5-methyl-3-oxo-1H-pyrazol-4-yl]diazenyl]-2-hydroxyphenyl]benzoic acid.

What is Eltrombopag Chloro Impurity used for?

Eltrombopag Chloro Impurity is supplied as a characterised reference material related to Eltrombopag. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Eltrombopag Chloro Impurity can I order?

We supply Eltrombopag Chloro Impurity in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Eltrombopag Chloro Impurity?

Yes. Every lot of Eltrombopag Chloro Impurity is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Eltrombopag Chloro Impurity be shipped internationally?

Yes. We export Eltrombopag Chloro Impurity worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.