3-Amino-2-hydroxy-[1,1-biphenyl]-3-carboxylic… 376592-93-7

Name: 3-Amino-2-hydroxy-[1,1-biphenyl]-3-carboxylic acid
Brand: Vaqora Chemicals
SKU: VQ-022504

About 3-Amino-2-hydroxy-[1,1-biphenyl]-3-carboxylic acid

Listed under CAS 376592-93-7, 3-Amino-2-hydroxy-[1,1-biphenyl]-3-carboxylic acid is a metabolite or degradation product of Eltrombopag available from Vaqora Chemicals. Formula C13H11NO3, molecular weight 229.23 g/mol. Its systematic (IUPAC) name is 3-(3-amino-2-hydroxyphenyl)benzoic acid. Common synonyms include 3'-Amino-2'-hydroxy-3-biphenylcarboxylic acid and CS-B0772.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. It carries the GHS signal word “Warning” with 4 hazard statements. Review the Safety Data Sheet before use.

It is used in metabolite identification, stability-indicating method development and impurity profiling of Eltrombopag, as well as in QC testing and ANDA/DMF documentation. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, 3-Amino-2-hydroxy-[1,1-biphenyl]-3-carboxylic acid is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling
Fine chemical synthesis

Industries

Related to Eltrombopag

View every impurity, metabolite and intermediate we list for Eltrombopag.

Eltrombopag impurities

Specifications & identifiers

Chemical identifiers
Product name	3-Amino-2-hydroxy-[1,1-biphenyl]-3-carboxylic acid
Catalogue No.	VQ-022504
CAS Number	376592-93-7
IUPAC name	3-(3-amino-2-hydroxyphenyl)benzoic acid
Molecular formula	C₁₃H₁₁NO₃
Molecular weight	229.23 g/mol
Exact mass	229.0739
Grade	Reference Standard
HSN code	38229090
InChIKey	ZXLYSSHNDUXXIN-UHFFFAOYSA-N
SMILES	C1=CC(=CC(=C1)C(=O)O)C2=C(C(=CC=C2)N)O
PubChem CID	11492332

Physical properties
Physical form	Solid
LogP (XLogP3)	2
H-bond donors / acceptors	3 / 4
TPSA	83.6 Å²
Synonyms	3'-Amino-2'-hydroxy-3-biphenylcarboxylic acid, CS-B0772, [1,1'-Biphenyl]-3-carboxylic acid, 3'-amino-2'-hydroxy-, 3-(3-amino-2-hydroxy-phenyl)benzoic Acid, [1,1'-Biphenyl]-3-carboxylicacid, 3'-amino-2'-hydroxy-, 3-amino-2-hydroxybiphenyl-3'-carboxylic acid

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 3-Amino-2-hydroxy-[1,1-biphenyl]-3-carboxylic acid?

The CAS Registry Number of 3-Amino-2-hydroxy-[1,1-biphenyl]-3-carboxylic acid is 376592-93-7. It is also known as 3'-Amino-2'-hydroxy-3-biphenylcarboxylic acid, CS-B0772, [1,1'-Biphenyl]-3-carboxylic acid, 3'-amino-2'-hydroxy-.

What is the molecular formula and molecular weight of 3-Amino-2-hydroxy-[1,1-biphenyl]-3-carboxylic acid?

3-Amino-2-hydroxy-[1,1-biphenyl]-3-carboxylic acid has the molecular formula C13H11NO3 and a molecular weight of 229.23 g/mol. Its IUPAC name is 3-(3-amino-2-hydroxyphenyl)benzoic acid.

What is 3-Amino-2-hydroxy-[1,1-biphenyl]-3-carboxylic acid used for?

3-Amino-2-hydroxy-[1,1-biphenyl]-3-carboxylic acid is supplied as a characterised reference material related to Eltrombopag. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 3-Amino-2-hydroxy-[1,1-biphenyl]-3-carboxylic acid can I order?

We supply 3-Amino-2-hydroxy-[1,1-biphenyl]-3-carboxylic acid in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 3-Amino-2-hydroxy-[1,1-biphenyl]-3-carboxylic acid?

Yes. Every lot of 3-Amino-2-hydroxy-[1,1-biphenyl]-3-carboxylic acid is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 3-Amino-2-hydroxy-[1,1-biphenyl]-3-carboxylic acid be shipped internationally?

Yes. 3-Amino-2-hydroxy-[1,1-biphenyl]-3-carboxylic acid is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.