4-Bromo-2,2-diphenylbutyric acid

Name: 4-Bromo-2,2-diphenylbutyric acid
Brand: Vaqora Chemicals
SKU: VQ-032401

About 4-Bromo-2,2-diphenylbutyric acid

Listed under CAS 37742-98-6, 4-Bromo-2,2-diphenylbutyric acid is a process intermediate or related compound of Loperamide available from Vaqora Chemicals. The compound has the formula C16H15BrO2, corresponding to a molecular weight of 319.19 g/mol. Systematically, it is named 4-bromo-2,2-diphenylbutanoic acid.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

It is a process intermediate or related compound in the synthesis of Loperamide, useful for route development, impurity fate-and-purge studies and analytical method development. It is used across pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, 4-Bromo-2,2-diphenylbutyric acid is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

API route development
Impurity fate & purge studies
Analytical method development
Fine chemical synthesis

Industries

Related to Loperamide

View every impurity, metabolite and intermediate we list for Loperamide.

Loperamide impurities

Specifications & identifiers

Chemical identifiers
Product name	4-Bromo-2,2-diphenylbutyric acid
Catalogue No.	VQ-032401
CAS Number	37742-98-6
IUPAC name	4-bromo-2,2-diphenylbutanoic acid
Molecular formula	C₁₆H₁₅BrO₂
Molecular weight	319.19 g/mol
Exact mass	318.0255
InChIKey	GFIYIIRFIODLLU-UHFFFAOYSA-N
SMILES	C1=CC=C(C=C1)C(CCBr)(C2=CC=CC=C2)C(=O)O
PubChem CID	2756959

Physical properties
Physical form	Solid
LogP (XLogP3)	4
H-bond donors / acceptors	1 / 2
TPSA	37.3 Å²

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P271, P280, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 4-Bromo-2,2-diphenylbutyric acid?

The CAS Registry Number of 4-Bromo-2,2-diphenylbutyric acid is 37742-98-6. It is also known as Benzeneacetic acid, a-(2-bromoethyl)-a-phenyl-.

What is the molecular formula and molecular weight of 4-Bromo-2,2-diphenylbutyric acid?

4-Bromo-2,2-diphenylbutyric acid has the molecular formula C16H15BrO2 and a molecular weight of 319.19 g/mol. Its IUPAC name is 4-bromo-2,2-diphenylbutanoic acid.

What is 4-Bromo-2,2-diphenylbutyric acid used for?

4-Bromo-2,2-diphenylbutyric acid is supplied as a characterised reference material related to Loperamide. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 4-Bromo-2,2-diphenylbutyric acid can I order?

We supply 4-Bromo-2,2-diphenylbutyric acid, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 4-Bromo-2,2-diphenylbutyric acid?

Yes. Every lot of 4-Bromo-2,2-diphenylbutyric acid is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 4-Bromo-2,2-diphenylbutyric acid be shipped internationally?

Yes. 4-Bromo-2,2-diphenylbutyric acid is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.