Dexamethasone Acid Impurity

Name: Dexamethasone Acid Impurity
Brand: Vaqora Chemicals
SKU: VQ-004782

About Dexamethasone Acid Impurity

Vaqora Chemicals supplies Dexamethasone Acid Impurity, an impurity of Dexamethasone registered under CAS number 37927-01-8 at a purity of 94%. Formula C21H27FO5, molecular weight 378.4 g/mol. It is also known as Dexamethasone Acid or (-)-Dexamethasone acid.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. It carries the GHS signal word “Danger” with 1 hazard statement. Review the Safety Data Sheet before use.

Pharmaceutical QC and development laboratories use this impurity standard of Dexamethasone to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide. Stock is available for quick dispatch.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Dexamethasone

View every impurity, metabolite and intermediate we list for Dexamethasone.

Dexamethasone impurities

Specifications & identifiers

Chemical identifiers
Product name	Dexamethasone Acid Impurity
Catalogue No.	VQ-004782
CAS Number	37927-01-8
IUPAC name	(8S,9R,10S,11S,13S,14S,16R,17R)-9-fluoro-11,17-dihydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthrene-17-carboxylic acid
Molecular formula	C₂₁H₂₇FO₅
Molecular weight	378.4 g/mol
Exact mass	378.1843
Grade	Reference Standard
Purity / assay	94%
HSN code	38229090
InChIKey	PFAGPIFFRLDBRN-AFKBWYBQSA-N
SMILES	C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@@]4([C@]3([C@H](C[C@@]2([C@]1(C(=O)O)O)C)O)F)C
PubChem CID	12878399

Physical properties
Physical form	Solid
LogP (XLogP3)	2
H-bond donors / acceptors	3 / 6
TPSA	94.8 Å²
Synonyms	Dexamethasone Acid, (-)-Dexamethasone acid, 9-Fluoro-11beta,17-dihydroxy-16alpha-methyl-3-oxoandrosta-1,4-diene-17beta-carboxylic acid, Dexamethasone Sodium Phosphate EP Impurity G, Betamethasone acid, (-)-, Dexamethasone Sodium phosphate Impurity G ((-)-Dexamethasone Acid), 9-Fluoro-11,17-dihydroxy-16a-methyl-3-oxoandrosta-1,4-diene-17-carboxylic Acid, 9-Fluoro-11b,17-dihydroxy-16a-methyl-3- oxoandrosta-1,4-diene-17b-carboxylic acid

Safety & hazard information (GHS)

Health hazard

Signal word: Danger

Hazard statements

H373May causes damage to organs through prolonged or repeated exposure

Precautionary statements: P203, P260, P280, P318, P319, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Dexamethasone Acid Impurity?

The CAS Registry Number of Dexamethasone Acid Impurity is 37927-01-8. It is also known as Dexamethasone Acid, (-)-Dexamethasone acid, 9-Fluoro-11beta,17-dihydroxy-16alpha-methyl-3-oxoandrosta-1,4-diene-17beta-carboxylic acid.

What is the molecular formula and molecular weight of Dexamethasone Acid Impurity?

Dexamethasone Acid Impurity has the molecular formula C21H27FO5 and a molecular weight of 378.4 g/mol. Its IUPAC name is (8S,9R,10S,11S,13S,14S,16R,17R)-9-fluoro-11,17-dihydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthrene-17-carboxylic acid.

What is Dexamethasone Acid Impurity used for?

Dexamethasone Acid Impurity is supplied as a characterised reference material related to Dexamethasone. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Dexamethasone Acid Impurity can I order?

We supply Dexamethasone Acid Impurity in Reference Standard (94%) grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Dexamethasone Acid Impurity?

Yes. Every lot of Dexamethasone Acid Impurity is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Dexamethasone Acid Impurity be shipped internationally?

Yes. Dexamethasone Acid Impurity is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.