Methyl (2-chloroacetyl)-L-prolinate

Name: Methyl (2-chloroacetyl)-L-prolinate
Brand: Vaqora Chemicals
SKU: VQ-034616

About Methyl (2-chloroacetyl)-L-prolinate

Vaqora Chemicals supplies Methyl (2-chloroacetyl)-L-prolinate, an impurity of Vildagliptin registered under CAS number 38074-72-5. Its molecular formula is C8H12ClNO3 and its molecular weight is 205.64 g/mol. Its systematic (IUPAC) name is methyl (2S)-1-(2-chloroacetyl)pyrrolidine-2-carboxylate. It is also known as N-chloroacetyl-L-proline methyl ester.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Good laboratory practice and suitable PPE are recommended during handling.

This Vildagliptin impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

We offer Methyl (2-chloroacetyl)-L-prolinate in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Vildagliptin

View every impurity, metabolite and intermediate we list for Vildagliptin.

Vildagliptin impurities

Specifications & identifiers

Chemical identifiers
Product name	Methyl (2-chloroacetyl)-L-prolinate
Catalogue No.	VQ-034616
CAS Number	38074-72-5
IUPAC name	methyl (2S)-1-(2-chloroacetyl)pyrrolidine-2-carboxylate
Molecular formula	C₈H₁₂ClNO₃
Molecular weight	205.64 g/mol
Exact mass	205.0506
Grade	Reference Standard
HSN code	38229090
InChIKey	YYUKRFPRBNDTQF-LURJTMIESA-N
SMILES	COC(=O)[C@@H]1CCCN1C(=O)CCl
PubChem CID	10798298

Physical properties
Physical form	Solid
LogP (XLogP3)	0.5
H-bond donors / acceptors	0 / 3
TPSA	46.6 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Methyl (2-chloroacetyl)-L-prolinate?

The CAS Registry Number of Methyl (2-chloroacetyl)-L-prolinate is 38074-72-5. It is also known as N-chloroacetyl-L-proline methyl ester, (S)-methyl 1-(2-chloroacetyl)pyrrolidine-2-carboxylate.

What is the molecular formula and molecular weight of Methyl (2-chloroacetyl)-L-prolinate?

Methyl (2-chloroacetyl)-L-prolinate has the molecular formula C8H12ClNO3 and a molecular weight of 205.64 g/mol. Its IUPAC name is methyl (2S)-1-(2-chloroacetyl)pyrrolidine-2-carboxylate.

What is Methyl (2-chloroacetyl)-L-prolinate used for?

Methyl (2-chloroacetyl)-L-prolinate is supplied as a characterised reference material related to Vildagliptin. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Methyl (2-chloroacetyl)-L-prolinate can I order?

We supply Methyl (2-chloroacetyl)-L-prolinate in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Methyl (2-chloroacetyl)-L-prolinate?

Yes. Every lot of Methyl (2-chloroacetyl)-L-prolinate is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Methyl (2-chloroacetyl)-L-prolinate be shipped internationally?

Yes. We export Methyl (2-chloroacetyl)-L-prolinate worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.