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(4R,6S)-6-(Chloromethyl)-4- hydroxytetrahydro-2H-pyran-2-one

Synonyms: 2H-Pyran-2-one, 6-(chloromethyl)tetrahydro-4-hydroxy-, (4R,6S)- · (4R,6S)-4-Hydroxy-6-chloromethyl-tetrahydropyran-2-one · (4R,6S)-6-(chloromethyl)-4-hydroxytetrahydropyran-2-one

CAS No.391218-14-7
FormulaC6H9ClO3
Mol. weight164.59
Catalogue No.VQ-033666
PurityReference Standard
HSN38229090

(4R,6S)-6-(Chloromethyl)-4- hydroxytetrahydro-2H-pyran-2-one (CAS 391218-14-7) – Rosuvastatin impurity standard. C6H9ClO3, MW 164.59. COA included.

Pack sizesPrice on quotation · bulk available
10 mg
25 mg
50 mg
100 mg
Bulk / custom pack · kg to MT
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Batch COA with every lot
16-section GHS SDS
Export to 120+ countries
DG-compliant packing

About (4R,6S)-6-(Chloromethyl)-4- hydroxytetrahydro-2H-pyran-2-one

Vaqora Chemicals supplies (4R,6S)-6-(Chloromethyl)-4- hydroxytetrahydro-2H-pyran-2-one, a metabolite or degradation product of Rosuvastatin registered under CAS number 391218-14-7. Its molecular formula is C6H9ClO3 and its molecular weight is 164.59 g/mol. The IUPAC name is (4R,6S)-6-(chloromethyl)-4-hydroxyoxan-2-one.

The product is provided as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Handle it with standard laboratory precautions and appropriate personal protective equipment.

Analytical teams use this compound to identify metabolites and degradants of Rosuvastatin, to validate stability-indicating methods (AMV) and to support QC and regulatory filings. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

We offer (4R,6S)-6-(Chloromethyl)-4- hydroxytetrahydro-2H-pyran-2-one in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

  • Metabolite identification
  • Stability-indicating methods
  • Impurity profiling

Industries

Related to Rosuvastatin

View every impurity, metabolite and intermediate we list for Rosuvastatin.

Rosuvastatin impurities

Specifications & identifiers

Chemical identifiers
Product name(4R,6S)-6-(Chloromethyl)-4- hydroxytetrahydro-2H-pyran-2-one
Catalogue No.VQ-033666
CAS Number391218-14-7
IUPAC name(4R,6S)-6-(chloromethyl)-4-hydroxyoxan-2-one
Molecular formulaC6H9ClO3
Molecular weight164.59 g/mol
Exact mass164.024
GradeReference Standard
HSN code38229090
InChIKeyKLWVUDQIPZIXER-UHNVWZDZSA-N
SMILESC1[C@H](CC(=O)O[C@@H]1CCl)O
PubChem CID10241131
Physical properties
Physical formSolid
LogP (XLogP3)0.2
H-bond donors / acceptors1 / 3
TPSA46.5 Ų

Documents

Frequently asked questions

What is the CAS number of (4R,6S)-6-(Chloromethyl)-4- hydroxytetrahydro-2H-pyran-2-one?

The CAS Registry Number of (4R,6S)-6-(Chloromethyl)-4- hydroxytetrahydro-2H-pyran-2-one is 391218-14-7. It is also known as 2H-Pyran-2-one, 6-(chloromethyl)tetrahydro-4-hydroxy-, (4R,6S)-, (4R,6S)-4-Hydroxy-6-chloromethyl-tetrahydropyran-2-one, (4R,6S)-6-(chloromethyl)-4-hydroxytetrahydropyran-2-one.

What is the molecular formula and molecular weight of (4R,6S)-6-(Chloromethyl)-4- hydroxytetrahydro-2H-pyran-2-one?

(4R,6S)-6-(Chloromethyl)-4- hydroxytetrahydro-2H-pyran-2-one has the molecular formula C6H9ClO3 and a molecular weight of 164.59 g/mol. Its IUPAC name is (4R,6S)-6-(chloromethyl)-4-hydroxyoxan-2-one.

What is (4R,6S)-6-(Chloromethyl)-4- hydroxytetrahydro-2H-pyran-2-one used for?

(4R,6S)-6-(Chloromethyl)-4- hydroxytetrahydro-2H-pyran-2-one is supplied as a characterised reference material related to Rosuvastatin. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of (4R,6S)-6-(Chloromethyl)-4- hydroxytetrahydro-2H-pyran-2-one can I order?

We supply (4R,6S)-6-(Chloromethyl)-4- hydroxytetrahydro-2H-pyran-2-one in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with (4R,6S)-6-(Chloromethyl)-4- hydroxytetrahydro-2H-pyran-2-one?

Yes. Every lot of (4R,6S)-6-(Chloromethyl)-4- hydroxytetrahydro-2H-pyran-2-one is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can (4R,6S)-6-(Chloromethyl)-4- hydroxytetrahydro-2H-pyran-2-one be shipped internationally?

Yes. We export (4R,6S)-6-(Chloromethyl)-4- hydroxytetrahydro-2H-pyran-2-one worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.

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