1-(Bromomethyl)-3-(trifluoromethyl)benzene

Name: 1-(Bromomethyl)-3-(trifluoromethyl)benzene
Brand: Vaqora Chemicals
SKU: VQ-012844

About 1-(Bromomethyl)-3-(trifluoromethyl)benzene

Listed under CAS 402-23-3, 1-(Bromomethyl)-3-(trifluoromethyl)benzene is a process intermediate or related compound of Siponimod available from Vaqora Chemicals. With the molecular formula C8H6BrF3, it has a molar mass of 239.03 g/mol. Alternative names: 3-(Bromomethyl)-1-(trifluoromethyl)benzene and 3-(Bromomethyl)benzotrifluoride.

It is supplied as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. Under GHS it is labelled “Danger”, so handle it with suitable PPE and consult the SDS.

Process chemists and analysts use it when developing synthetic routes to Siponimod, tracking process-related impurities and validating analytical methods. It is used across pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

API route development
Impurity fate & purge studies
Analytical method development

Industries

Related to Siponimod

View every impurity, metabolite and intermediate we list for Siponimod.

Siponimod impurities

Specifications & identifiers

Chemical identifiers
Product name	1-(Bromomethyl)-3-(trifluoromethyl)benzene
Catalogue No.	VQ-012844
CAS Number	402-23-3
IUPAC name	1-(bromomethyl)-3-(trifluoromethyl)benzene
Molecular formula	C₈H₆BrF₃
Molecular weight	239.03 g/mol
Exact mass	237.9605
Grade	Reference Standard
InChIKey	MYYYZNVAUZVXBO-UHFFFAOYSA-N
SMILES	C1=CC(=CC(=C1)C(F)(F)F)CBr
PubChem CID	123061

Physical properties
Physical form	Solid
LogP (XLogP3)	3.7
H-bond donors / acceptors	0 / 3
TPSA	0 Å²
Synonyms	3-(Bromomethyl)-1-(trifluoromethyl)benzene, 3-(Bromomethyl)benzotrifluoride, 3-(Trifluoromethyl)benzyl bromide, m-(Trifluoromethyl)benzyl bromide, m-Trifluoromethylbenzyl bromide, 3-Trifluoromethylbenzyl bromide, 1-bromomethyl-3-trifluoromethyl-benzene, 3-(trifluoromethyl)benzylbromide, alpha'-Bromo-alpha,alpha,alpha-trifluoro-m-xylene, Benzene, 1-(bromomethyl)-3-(trifluoromethyl)-, 3-trifluormethyl benzylbromide, 3-trifluoromethyl-benzyl bromide

Safety & hazard information (GHS)

Corrosive

Signal word: Danger

Hazard statements

H314Causes severe skin burns and eye damage

Precautionary statements: P260, P264, P280, P301 + P330 + P331, P302 + P361 + P354, P304 + P340, P305 + P354 + P338, P316, P321, P363, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 1-(Bromomethyl)-3-(trifluoromethyl)benzene?

The CAS Registry Number of 1-(Bromomethyl)-3-(trifluoromethyl)benzene is 402-23-3. It is also known as 3-(Bromomethyl)-1-(trifluoromethyl)benzene, 3-(Bromomethyl)benzotrifluoride, 3-(Trifluoromethyl)benzyl bromide.

What is the molecular formula and molecular weight of 1-(Bromomethyl)-3-(trifluoromethyl)benzene?

1-(Bromomethyl)-3-(trifluoromethyl)benzene has the molecular formula C8H6BrF3 and a molecular weight of 239.03 g/mol. Its IUPAC name is 1-(bromomethyl)-3-(trifluoromethyl)benzene.

What is 1-(Bromomethyl)-3-(trifluoromethyl)benzene used for?

1-(Bromomethyl)-3-(trifluoromethyl)benzene is supplied as a characterised reference material related to Siponimod. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 1-(Bromomethyl)-3-(trifluoromethyl)benzene can I order?

We supply 1-(Bromomethyl)-3-(trifluoromethyl)benzene in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 1-(Bromomethyl)-3-(trifluoromethyl)benzene?

Yes. Every lot of 1-(Bromomethyl)-3-(trifluoromethyl)benzene is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 1-(Bromomethyl)-3-(trifluoromethyl)benzene be shipped internationally?

Yes. 1-(Bromomethyl)-3-(trifluoromethyl)benzene is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.