Lenvatinib

Name: Lenvatinib
Brand: Vaqora Chemicals
SKU: VQ-007533

About Lenvatinib

Vaqora Chemicals supplies Lenvatinib, a high-purity reference standard of Lenvatinib registered under CAS number 417716-92-8. With the molecular formula C21H19ClN4O4, it has a molar mass of 426.9 g/mol. The IUPAC name is 4-[3-chloro-4-(cyclopropylcarbamoylamino)phenoxy]-7-methoxyquinoline-6-carboxamide. Alternative names: Lenvanix and Multi-Kinase Inhibitor E7080.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

As a reference sample of Lenvatinib, it is used for identification, assay and impurity-profiling work during analytical method development, validation (AMV) and routine QC. It is used across pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide. Stock is available for quick dispatch.

Typical applications

Identification & assay
Method development & validation
QC reference material

Industries

Related to Lenvatinib

View every impurity, metabolite and intermediate we list for Lenvatinib.

Lenvatinib impurities

Specifications & identifiers

Chemical identifiers
Product name	Lenvatinib
Catalogue No.	VQ-007533
CAS Number	417716-92-8
Other CAS	857890-39-2
IUPAC name	4-[3-chloro-4-(cyclopropylcarbamoylamino)phenoxy]-7-methoxyquinoline-6-carboxamide
Molecular formula	C₂₁H₁₉ClN₄O₄
Molecular weight	426.9 g/mol
Exact mass	426.1095
Grade	Reference Standard
HSN code	38229090
InChIKey	WOSKHXYHFSIKNG-UHFFFAOYSA-N
SMILES	COC1=CC2=NC=CC(=C2C=C1C(=O)N)OC3=CC(=C(C=C3)NC(=O)NC4CC4)Cl
PubChem CID	9823820

Physical properties
Physical form	Solid
LogP (XLogP3)	2.8
H-bond donors / acceptors	3 / 5
TPSA	116 Å²
Synonyms	4-[3-Chloro-4-[[(cyclopropylamino)carbonyl]amino]phenoxy]-7-methoxy-6-quinolinecarboxamide, 4-(3-Chloro-4-(3-cyclopropylureido)phenoxy)-7-methoxyquinoline-6-carboxamide, Lenvanix, 4-{3-Chloro-4-[(Cyclopropylcarbamoyl)amino]phenoxy}-7-Methoxyquinoline-6-Carboxamide, 4-(3-chloro-4-(N'-cyclopropylureido)phenoxy)-7-methoxyquinoline-6-carboxamide, 4-(3-chloro-4-((cyclopropylaminocarbonyl)amino)phenoxy)-7-methoxy-6-quinolinecarboxamide, 4-(3-chloro-4-(cyclopropylcarbamoylamino)phenoxy)-7-methoxyquinoline-6-carboxamide, Multi-Kinase Inhibitor E7080, E7080 (Lenvatinib), Lenvatinib (E7080), Lenvatinib free base, C21H19ClN4O4

Safety & hazard information (GHS)

Harmful / irritant

Health hazard

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
H361Suspected of damaging fertility or the unborn child

Precautionary statements: P203, P261, P264, P264 + P265, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P305 + P351 + P338, P318, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Lenvatinib?

The CAS Registry Number of Lenvatinib is 417716-92-8. It is also known as 4-[3-Chloro-4-[[(cyclopropylamino)carbonyl]amino]phenoxy]-7-methoxy-6-quinolinecarboxamide, 4-(3-Chloro-4-(3-cyclopropylureido)phenoxy)-7-methoxyquinoline-6-carboxamide, Lenvanix.

What is the molecular formula and molecular weight of Lenvatinib?

Lenvatinib has the molecular formula C21H19ClN4O4 and a molecular weight of 426.9 g/mol. Its IUPAC name is 4-[3-chloro-4-(cyclopropylcarbamoylamino)phenoxy]-7-methoxyquinoline-6-carboxamide.

What is Lenvatinib used for?

Lenvatinib is supplied as a characterised reference material related to Lenvatinib. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Lenvatinib can I order?

We supply Lenvatinib in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg, 250 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Lenvatinib?

Yes. Every lot of Lenvatinib is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Lenvatinib be shipped internationally?

Yes. Lenvatinib is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.