N,N-Bis(2-chloroethyl)-p-toluenesulfonamide

About N,N-Bis(2-chloroethyl)-p-toluenesulfonamide

N,N-Bis(2-chloroethyl)-p-toluenesulfonamide is an impurity of Cetirizine carrying the CAS registry number 42137-88-2. Formula C11H15Cl2NO2S, molecular weight 296.2 g/mol. Its systematic (IUPAC) name is N,N-bis(2-chloroethyl)-4-methylbenzenesulfonamide. Common synonyms include 2-Chloro-N-(2-chloroethyl)-N-tosylethanamine and N,N-Bis(2-chloroethyl)-p-toluenesulphonamide.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Under GHS it is labelled “Danger”, so handle it with suitable PPE and consult the SDS.

Pharmaceutical QC and development laboratories use this impurity standard of Cetirizine to develop and validate HPLC methods, to set specification limits and to document impurity profiles in ANDA and DMF submissions. It is used across pharmaceutical manufacturing and academic and industrial research.

We offer N,N-Bis(2-chloroethyl)-p-toluenesulfonamide in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Cetirizine

View every impurity, metabolite and intermediate we list for Cetirizine.

Cetirizine impurities

Specifications & identifiers

Chemical identifiers
Product name	N,N-Bis(2-chloroethyl)-p-toluenesulfonamide
Catalogue No.	VQ-031520
CAS Number	42137-88-2
IUPAC name	N,N-bis(2-chloroethyl)-4-methylbenzenesulfonamide
Molecular formula	C₁₁H₁₅Cl₂NO₂S
Molecular weight	296.2 g/mol
Exact mass	295.0201
Grade	Reference Standard
HSN code	38229090
InChIKey	PTVBBIMKLOMGSY-UHFFFAOYSA-N
SMILES	CC1=CC=C(C=C1)S(=O)(=O)N(CCCl)CCCl
PubChem CID	96039

Physical properties
Physical form	Solid
LogP (XLogP3)	2.6
H-bond donors / acceptors	0 / 3
TPSA	45.8 Å²
Synonyms	2-Chloro-N-(2-chloroethyl)-N-tosylethanamine, N,N-Bis(2-chloroethyl)-p-toluenesulphonamide, N,N-bis(2-chloroethyl)-4-methylbenzene-1-sulfonamide, Benzenesulfonamide, N,N-bis(2-chloroethyl)-4-methyl-, N,N-Bis(.beta.-chloroethyl)-p-toluenesulfonamide, N,N-bis(2-chloroethyl)-4-toluenesulfonamide, N,N-Bis(2-chloroethyl)-4-methylbenzensulfonamide, N,N-bis(2'-chloroethyl)-4-methylbenzenesulfonamide, N,N-bis(2-chloroethyl)-4-methyl-benzenesulfonamide, N,N-bis(2-chloroethyl)-4-methylbenzene sulfonamide, N,N-bis(2-chloroethyl)-4-methylbenzene sulphonamide

Safety & hazard information (GHS)

Toxic

Harmful / irritant

Signal word: Danger

Hazard statements

H301Toxic if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P270, P271, P280, P301 + P316, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P330, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of N,N-Bis(2-chloroethyl)-p-toluenesulfonamide?

The CAS Registry Number of N,N-Bis(2-chloroethyl)-p-toluenesulfonamide is 42137-88-2. It is also known as 2-Chloro-N-(2-chloroethyl)-N-tosylethanamine, N,N-Bis(2-chloroethyl)-p-toluenesulphonamide, N,N-bis(2-chloroethyl)-4-methylbenzene-1-sulfonamide.

What is the molecular formula and molecular weight of N,N-Bis(2-chloroethyl)-p-toluenesulfonamide?

N,N-Bis(2-chloroethyl)-p-toluenesulfonamide has the molecular formula C11H15Cl2NO2S and a molecular weight of 296.2 g/mol. Its IUPAC name is N,N-bis(2-chloroethyl)-4-methylbenzenesulfonamide.

What is N,N-Bis(2-chloroethyl)-p-toluenesulfonamide used for?

N,N-Bis(2-chloroethyl)-p-toluenesulfonamide is supplied as a characterised reference material related to Cetirizine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of N,N-Bis(2-chloroethyl)-p-toluenesulfonamide can I order?

We supply N,N-Bis(2-chloroethyl)-p-toluenesulfonamide in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with N,N-Bis(2-chloroethyl)-p-toluenesulfonamide?

Yes. Every lot of N,N-Bis(2-chloroethyl)-p-toluenesulfonamide is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can N,N-Bis(2-chloroethyl)-p-toluenesulfonamide be shipped internationally?

Yes. N,N-Bis(2-chloroethyl)-p-toluenesulfonamide is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.