Nornalmefene

About Nornalmefene

Nornalmefene is a process intermediate or related compound of Nalmefene carrying the CAS registry number 42971-33-5. With the molecular formula C17H19NO3, it has a molar mass of 285.34 g/mol. Systematically, it is named (4R,4aS,7aS,12bS)-7-methylidene-1,2,3,4,5,6,7a,13-octahydro-4,12-methanobenzofuro[3,2-e]isoquinoline-4a,9-diol. Common synonyms include 6-Methylene noroxymorphone.

It is supplied as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Handle it with standard laboratory precautions and appropriate personal protective equipment.

It is a process intermediate or related compound in the synthesis of Nalmefene, useful for route development, impurity fate-and-purge studies and analytical method development. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Standard pack sizes are 10 mg, 25 mg, 50 mg and 100 mg, and every batch ships with a Certificate of Analysis (COA) and we export worldwide.

Typical applications

API route development
Impurity fate & purge studies
Analytical method development
Fine chemical synthesis

Industries

Related to Nalmefene

View every impurity, metabolite and intermediate we list for Nalmefene.

Nalmefene impurities

Specifications & identifiers

Chemical identifiers
Product name	Nornalmefene
Catalogue No.	VQ-049189
CAS Number	42971-33-5
IUPAC name	(4R,4aS,7aS,12bS)-7-methylidene-1,2,3,4,5,6,7a,13-octahydro-4,12-methanobenzofuro[3,2-e]isoquinoline-4a,9-diol
Molecular formula	C₁₇H₁₉NO₃
Molecular weight	285.34 g/mol
Exact mass	285.1365
HSN code	2933
InChIKey	QUXLQAACGCFFEX-ISWURRPUSA-N
SMILES	C=C1CC[C@]2([C@H]3CC4=C5[C@]2([C@H]1OC5=C(C=C4)O)CCN3)O
PubChem CID	9971176

Physical properties
Physical form	Solid
LogP (XLogP3)	1.1
H-bond donors / acceptors	3 / 4
TPSA	61.7 Å²

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Nornalmefene?

The CAS Registry Number of Nornalmefene is 42971-33-5. It is also known as 6-Methylene noroxymorphone, 6-Deoxydihydro-14-hydroxy-6-methylene normorphine, Morphinan-3,14-diol, 4,5-epoxy-6-methylene-, (5alpha)-.

What is the molecular formula and molecular weight of Nornalmefene?

Nornalmefene has the molecular formula C17H19NO3 and a molecular weight of 285.34 g/mol. Its IUPAC name is (4R,4aS,7aS,12bS)-7-methylidene-1,2,3,4,5,6,7a,13-octahydro-4,12-methanobenzofuro[3,2-e]isoquinoline-4a,9-diol.

What is Nornalmefene used for?

Nornalmefene is supplied as a characterised reference material related to Nalmefene. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Nornalmefene can I order?

We supply Nornalmefene, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Nornalmefene?

Yes. Every lot of Nornalmefene is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Nornalmefene be shipped internationally?

Yes. We export Nornalmefene worldwide by air and sea freight or express courier, on EXW, FOB, CIF, CFR or DAP Incoterms, with full export documentation.