1-(4-tert-Butylphenyl)-4-chloro-1-butanone

Name: 1-(4-tert-Butylphenyl)-4-chloro-1-butanone
Brand: Vaqora Chemicals
SKU: VQ-042446

About 1-(4-tert-Butylphenyl)-4-chloro-1-butanone

Listed under CAS 43076-61-5, 1-(4-tert-Butylphenyl)-4-chloro-1-butanone is a process intermediate or related compound of Terfenadine available from Vaqora Chemicals. Its molecular formula is C14H19ClO and its molecular weight is 238.75 g/mol. The IUPAC name is 1-(4-tert-butylphenyl)-4-chlorobutan-1-one. It is also known as 4'-tert-Butyl-4-chlorobutyrophenone or 1-(4-(tert-Butyl)phenyl)-4-chlorobutan-1-one.

It is supplied as a solid. Store the standard in its sealed vial, protected from light and moisture, and follow the storage condition printed on the COA. Under GHS it is labelled “Danger”, so handle it with suitable PPE and consult the SDS.

It is a process intermediate or related compound in the synthesis of Terfenadine, useful for route development, impurity fate-and-purge studies and analytical method development. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

Available in 10 mg, 25 mg, 50 mg and 100 mg packs, 1-(4-tert-Butylphenyl)-4-chloro-1-butanone is dispatched with a Certificate of Analysis (COA) to destinations worldwide.

Typical applications

API route development
Impurity fate & purge studies
Analytical method development
Fine chemical synthesis

Industries

Related to Terfenadine

View every impurity, metabolite and intermediate we list for Terfenadine.

Terfenadine impurities

Specifications & identifiers

Chemical identifiers
Product name	1-(4-tert-Butylphenyl)-4-chloro-1-butanone
Catalogue No.	VQ-042446
CAS Number	43076-61-5
IUPAC name	1-(4-tert-butylphenyl)-4-chlorobutan-1-one
Molecular formula	C₁₄H₁₉ClO
Molecular weight	238.75 g/mol
Exact mass	238.1124
InChIKey	RLKSQLJFGCDUOX-UHFFFAOYSA-N
SMILES	CC(C)(C)C1=CC=C(C=C1)C(=O)CCCCl
PubChem CID	2723694

Physical properties
Physical form	Solid
LogP (XLogP3)	4.2
H-bond donors / acceptors	0 / 1
TPSA	17.1 Å²
Synonyms	4'-tert-Butyl-4-chlorobutyrophenone, 1-(4-(tert-Butyl)phenyl)-4-chlorobutan-1-one, 1-Butanone, 4-chloro-1-[4-(1,1-dimethylethyl)phenyl]-, 4-Chloro-4'-tert-butylbutyrophenone, 1-[4-(tert-butyl)phenyl]-4-chlorobutan-1-one, 4'-tertbutyl-4-chlorobutyrophenone, 4-Chloro-1-[4-(1,1-dimethylethyl)phenyl]- 1-butanone, butyrophenone derivative, 1-(4-Tert-Butyl-phenyl)-4-chloro-butan-1-one, p-t-butyl-gamma-chlorobutyrophenone, 4'-Tert Butyl-4-Chlorobutyrophenone

Safety & hazard information (GHS)

Corrosive

Harmful / irritant

Environmental hazard

Signal word: Danger

Hazard statements

H302Harmful if swallowed
H317May cause an allergic skin reaction
H318Causes serious eye damage
H411Toxic to aquatic life with long lasting effects

Precautionary statements: P261, P264, P264 + P265, P270, P272, P273, P280, P301 + P317, P302 + P352, P305 + P354 + P338, P317, P321, P330, P333 + P317, P362 + P364, P391, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 1-(4-tert-Butylphenyl)-4-chloro-1-butanone?

The CAS Registry Number of 1-(4-tert-Butylphenyl)-4-chloro-1-butanone is 43076-61-5. It is also known as 4'-tert-Butyl-4-chlorobutyrophenone, 1-(4-(tert-Butyl)phenyl)-4-chlorobutan-1-one, 1-Butanone, 4-chloro-1-[4-(1,1-dimethylethyl)phenyl]-.

What is the molecular formula and molecular weight of 1-(4-tert-Butylphenyl)-4-chloro-1-butanone?

1-(4-tert-Butylphenyl)-4-chloro-1-butanone has the molecular formula C14H19ClO and a molecular weight of 238.75 g/mol. Its IUPAC name is 1-(4-tert-butylphenyl)-4-chlorobutan-1-one.

What is 1-(4-tert-Butylphenyl)-4-chloro-1-butanone used for?

1-(4-tert-Butylphenyl)-4-chloro-1-butanone is supplied as a characterised reference material related to Terfenadine. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 1-(4-tert-Butylphenyl)-4-chloro-1-butanone can I order?

We supply 1-(4-tert-Butylphenyl)-4-chloro-1-butanone, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 1-(4-tert-Butylphenyl)-4-chloro-1-butanone?

Yes. Every lot of 1-(4-tert-Butylphenyl)-4-chloro-1-butanone is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 1-(4-tert-Butylphenyl)-4-chloro-1-butanone be shipped internationally?

Yes. 1-(4-tert-Butylphenyl)-4-chloro-1-butanone is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.