4-Methylphthalic Acid

About 4-Methylphthalic Acid

4-Methylphthalic Acid is an impurity of Alogliptin carrying the CAS registry number 4316-23-8. Formula C9H8O4, molecular weight 180.16 g/mol. Alternative names: Phthalic acid, 4-methyl- and 1,2-Benzenedicarboxylic acid, 4-methyl-.

The product is provided as a solid. Reference materials should be stored sealed and away from light and moisture, as specified on the accompanying COA. The GHS classification uses the signal word “Warning”, so appropriate gloves, eye protection and ventilation are recommended.

This Alogliptin impurity supports analytical method development and validation (AMV), batch release testing and the impurity sections of ANDA and DMF filings. Typical end-use sectors are pharmaceutical manufacturing and academic and industrial research.

We offer 4-Methylphthalic Acid in 10 mg, 25 mg, 50 mg and 100 mg packs with a batch-specific COA, and ship to customers worldwide.

Typical applications

Analytical method development
Method validation (AMV)
QC release testing
ANDA / DMF filings

Industries

Related to Alogliptin

View every impurity, metabolite and intermediate we list for Alogliptin.

Alogliptin impurities

Specifications & identifiers

Chemical identifiers
Product name	4-Methylphthalic Acid
Catalogue No.	VQ-023392
CAS Number	4316-23-8
IUPAC name	4-methylphthalic acid
Molecular formula	C₉H₈O₄
Molecular weight	180.16 g/mol
Exact mass	180.0423
Grade	Reference Standard
HSN code	38229090
InChIKey	CWJJAFQCTXFSTA-UHFFFAOYSA-N
SMILES	CC1=CC(=C(C=C1)C(=O)O)C(=O)O
PubChem CID	20310

Physical properties
Physical form	Solid
LogP (XLogP3)	2.3
H-bond donors / acceptors	2 / 4
TPSA	74.6 Å²
Synonyms	Phthalic acid, 4-methyl-, 1,2-Benzenedicarboxylic acid, 4-methyl-, 4-Methyl-o-phthalate, 4-Methyl-1,2-benzenedicarboxylic acid, 4-methylbenzene-1,2-dicarboxylic acid

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements: P261, P264, P264 + P265, P271, P280, P302 + P352, P304 + P340, P305 + P351 + P338, P319, P321, P332 + P317, P337 + P317, P362 + P364, P403 + P233, P405, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of 4-Methylphthalic Acid?

The CAS Registry Number of 4-Methylphthalic Acid is 4316-23-8. It is also known as Phthalic acid, 4-methyl-, 1,2-Benzenedicarboxylic acid, 4-methyl-, 4-Methyl-o-phthalate.

What is the molecular formula and molecular weight of 4-Methylphthalic Acid?

4-Methylphthalic Acid has the molecular formula C9H8O4 and a molecular weight of 180.16 g/mol. Its IUPAC name is 4-methylphthalic acid.

What is 4-Methylphthalic Acid used for?

4-Methylphthalic Acid is supplied as a characterised reference material related to Alogliptin. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of 4-Methylphthalic Acid can I order?

We supply 4-Methylphthalic Acid in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with 4-Methylphthalic Acid?

Yes. Every lot of 4-Methylphthalic Acid is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can 4-Methylphthalic Acid be shipped internationally?

Yes. 4-Methylphthalic Acid is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.