Methyl 2-amino-2-(4-hydroxyphenyl)acetate

Name: Methyl 2-amino-2-(4-hydroxyphenyl)acetate
Brand: Vaqora Chemicals
SKU: VQ-029147

About Methyl 2-amino-2-(4-hydroxyphenyl)acetate

Vaqora Chemicals supplies Methyl 2-amino-2-(4-hydroxyphenyl)acetate, a metabolite or degradation product of Amoxicillin registered under CAS number 43189-12-4. Its molecular formula is C9H11NO3 and its molecular weight is 181.19 g/mol. It is also known as PHPGME cpd or p-hydroxyphenylglycine methyl ester.

The product is provided as a solid. Keep the vial tightly closed, protected from light and humidity, at the temperature stated on the Certificate of Analysis. Under GHS it is labelled “Warning”, so handle it with suitable PPE and consult the SDS.

It is used in metabolite identification, stability-indicating method development and impurity profiling of Amoxicillin, as well as in QC testing and ANDA/DMF documentation. Buyers come mainly from pharmaceutical manufacturing and academic and industrial research.

Vaqora Chemicals supplies Methyl 2-amino-2-(4-hydroxyphenyl)acetate in 10 mg, 25 mg, 50 mg and 100 mg packs, each shipped with a Certificate of Analysis (COA), and exports worldwide.

Typical applications

Metabolite identification
Stability-indicating methods
Impurity profiling

Industries

Related to Amoxicillin

View every impurity, metabolite and intermediate we list for Amoxicillin.

Amoxicillin impurities

Specifications & identifiers

Chemical identifiers
Product name	Methyl 2-amino-2-(4-hydroxyphenyl)acetate
Catalogue No.	VQ-029147
CAS Number	43189-12-4
IUPAC name	methyl 2-amino-2-(4-hydroxyphenyl)acetate
Molecular formula	C₉H₁₁NO₃
Molecular weight	181.19 g/mol
Exact mass	181.0739
Grade	Reference Standard
HSN code	38229090
InChIKey	SZBDOFWNZVHVGR-UHFFFAOYSA-N
SMILES	COC(=O)C(C1=CC=C(C=C1)O)N
PubChem CID	4123006

Physical properties
Physical form	Solid
LogP (XLogP3)	0.5
H-bond donors / acceptors	2 / 4
TPSA	72.6 Å²
Synonyms	PHPGME cpd, p-hydroxyphenylglycine methyl ester, Benzeneacetic acid, a-amino-4-hydroxy-, methyl ester, (aR)-, benzeneacetic acid, alpha-amino-4-hydroxy-, methyl ester monohydrochloride, methyl amino(4-hydroxyphenyl)acetate, d-2-(4-hydroxyphenyl)glycine methyl ester, amino-(4-hydroxy-phenyl)-acetic acid methyl ester, methyl alpha-amino-alpha-(4-hydroxyphenyl)acetate

Safety & hazard information (GHS)

Harmful / irritant

Signal word: Warning

Hazard statements

H302Harmful if swallowed
H312Harmful in contact with skin
H332Harmful if inhaled

Precautionary statements: P261, P264, P270, P271, P280, P301 + P317, P302 + P352, P304 + P340, P317, P321, P330, P362 + P364, P501

Classification is indicative (aggregated GHS notifications) and may vary by grade and concentration. Always refer to the SDS supplied with your lot.

Documents

Safety Data Sheet (SDS)16-section GHS · on request Certificate of AnalysisTypical / batch COA · on request Specification sheetTDS / MOA · on request

Frequently asked questions

What is the CAS number of Methyl 2-amino-2-(4-hydroxyphenyl)acetate?

The CAS Registry Number of Methyl 2-amino-2-(4-hydroxyphenyl)acetate is 43189-12-4. It is also known as PHPGME cpd, p-hydroxyphenylglycine methyl ester, Benzeneacetic acid, a-amino-4-hydroxy-, methyl ester, (aR)-.

What is the molecular formula and molecular weight of Methyl 2-amino-2-(4-hydroxyphenyl)acetate?

Methyl 2-amino-2-(4-hydroxyphenyl)acetate has the molecular formula C9H11NO3 and a molecular weight of 181.19 g/mol. Its IUPAC name is methyl 2-amino-2-(4-hydroxyphenyl)acetate.

What is Methyl 2-amino-2-(4-hydroxyphenyl)acetate used for?

Methyl 2-amino-2-(4-hydroxyphenyl)acetate is supplied as a characterised reference material related to Amoxicillin. It is used for analytical method development and validation (AMV), impurity profiling, stability studies and quality control, and in ANDA/DMF regulatory filings.

Which grade and pack sizes of Methyl 2-amino-2-(4-hydroxyphenyl)acetate can I order?

We supply Methyl 2-amino-2-(4-hydroxyphenyl)acetate in Reference Standard grade, in 10 mg, 25 mg, 50 mg, 100 mg packs. Larger bulk quantities and custom packing are quoted on request.

Do you provide a COA and SDS with Methyl 2-amino-2-(4-hydroxyphenyl)acetate?

Yes. Every lot of Methyl 2-amino-2-(4-hydroxyphenyl)acetate is shipped with a batch-specific Certificate of Analysis, and a 16-section GHS Safety Data Sheet is provided with the quotation and the shipment.

Can Methyl 2-amino-2-(4-hydroxyphenyl)acetate be shipped internationally?

Yes. Methyl 2-amino-2-(4-hydroxyphenyl)acetate is classified as hazardous, so it is packed in UN-approved packaging and shipped as dangerous goods under IATA/IMDG rules. We export worldwide on EXW, FOB, CIF and DAP terms.